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Interleukin-18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis.
Knorr J, Kaufmann B, Inzaugarat ME, Holtmann TM, Geisler L, Hundertmark J, Kohlhepp MS, Boosheri LM, Chilin-Fuentes DR, Birmingham A, Fisch KM, Schilling JD, Loosen SH, Trautwein C, Roderburg C, Demir M, Tacke F, Hoffman HM, Feldstein AE, Wree A. Knorr J, et al. Among authors: hoffman hm. Hepatology. 2023 Jun 1;77(6):1968-1982. doi: 10.1002/hep.32776. Epub 2022 Oct 12. Hepatology. 2023. PMID: 36059147 Free PMC article.
From NAFLD to NASH to cirrhosis-new insights into disease mechanisms.
Wree A, Broderick L, Canbay A, Hoffman HM, Feldstein AE. Wree A, et al. Among authors: hoffman hm. Nat Rev Gastroenterol Hepatol. 2013 Nov;10(11):627-36. doi: 10.1038/nrgastro.2013.149. Epub 2013 Aug 20. Nat Rev Gastroenterol Hepatol. 2013. PMID: 23958599 Review.
NLRP3 inflammasome activation is required for fibrosis development in NAFLD.
Wree A, McGeough MD, Peña CA, Schlattjan M, Li H, Inzaugarat ME, Messer K, Canbay A, Hoffman HM, Feldstein AE. Wree A, et al. Among authors: hoffman hm. J Mol Med (Berl). 2014 Oct;92(10):1069-82. doi: 10.1007/s00109-014-1170-1. Epub 2014 May 28. J Mol Med (Berl). 2014. PMID: 24861026 Free PMC article.
NLRP3 inflammasome driven liver injury and fibrosis: Roles of IL-17 and TNF in mice.
Wree A, McGeough MD, Inzaugarat ME, Eguchi A, Schuster S, Johnson CD, Peña CA, Geisler LJ, Papouchado BG, Hoffman HM, Feldstein AE. Wree A, et al. Among authors: hoffman hm. Hepatology. 2018 Feb;67(2):736-749. doi: 10.1002/hep.29523. Epub 2017 Dec 28. Hepatology. 2018. PMID: 28902427 Free PMC article.
Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis.
Gaul S, Leszczynska A, Alegre F, Kaufmann B, Johnson CD, Adams LA, Wree A, Damm G, Seehofer D, Calvente CJ, Povero D, Kisseleva T, Eguchi A, McGeough MD, Hoffman HM, Pelegrin P, Laufs U, Feldstein AE. Gaul S, et al. Among authors: hoffman hm. J Hepatol. 2021 Jan;74(1):156-167. doi: 10.1016/j.jhep.2020.07.041. Epub 2020 Aug 4. J Hepatol. 2021. PMID: 32763266 Free PMC article.
182 results