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IFITM3 restricts virus-induced inflammatory cytokine production by limiting Nogo-B mediated TLR responses.
Clement M, Forbester JL, Marsden M, Sabberwal P, Sommerville MS, Wellington D, Dimonte S, Clare S, Harcourt K, Yin Z, Nobre L, Antrobus R, Jin B, Chen M, Makvandi-Nejad S, Lindborg JA, Strittmatter SM, Weekes MP, Stanton RJ, Dong T, Humphreys IR. Clement M, et al. Among authors: makvandi nejad s. Nat Commun. 2022 Sep 8;13(1):5294. doi: 10.1038/s41467-022-32587-4. Nat Commun. 2022. PMID: 36075894 Free PMC article.
IFITM3-specific antibody reveals IFN preferences and slow IFN induction of the antiviral factor IFITM3 in humans.
Wellington D, Yin Z, Abdel-Haq A, Zhang L, Forbester J, Kite K, Rajapaksa U, Laurenson-Schafer H, Makvandi-Nejad S, Jin B, Bowes E, Manoharan K, Maldonado-Perez D, Verrill C, Humphreys IR, Dong T. Wellington D, et al. Among authors: makvandi nejad s. Eur J Immunol. 2021 Mar;51(3):742-745. doi: 10.1002/eji.202048706. Epub 2020 Dec 9. Eur J Immunol. 2021. PMID: 33125710 Free PMC article.
A Novel Vaccine Strategy Employing Serologically Different Chimpanzee Adenoviral Vectors for the Prevention of HIV-1 and HCV Coinfection.
Hartnell F, Brown A, Capone S, Kopycinski J, Bliss C, Makvandi-Nejad S, Swadling L, Ghaffari E, Cicconi P, Del Sorbo M, Sbrocchi R, Esposito I, Vassilev V, Marriott P, Gardiner CM, Bannan C, Bergin C, Hoffmann M, Turner B, Nicosia A, Folgori A, Hanke T, Barnes E, Dorrell L. Hartnell F, et al. Front Immunol. 2019 Jan 18;9:3175. doi: 10.3389/fimmu.2018.03175. eCollection 2018. Front Immunol. 2019. PMID: 30713538 Free PMC article. Clinical Trial.
26 results