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Page 1
Stromal Reprogramming by FAK Inhibition Overcomes Radiation Resistance to Allow for Immune Priming and Response to Checkpoint Blockade.
Lander VE, Belle JI, Kingston NL, Herndon JM, Hogg GD, Liu X, Kang LI, Knolhoff BL, Bogner SJ, Baer JM, Zuo C, Borcherding NC, Lander DP, Mpoy C, Scott J, Zahner M, Rogers BE, Schwarz JK, Kim H, DeNardo DG. Lander VE, et al. Cancer Discov. 2022 Dec 2;12(12):2774-2799. doi: 10.1158/2159-8290.CD-22-0192. Cancer Discov. 2022. PMID: 36165893 Free PMC article.
Stromal and therapy-induced macrophage proliferation promotes PDAC progression and susceptibility to innate immunotherapy.
Zuo C, Baer JM, Knolhoff BL, Belle JI, Liu X, Alarcon De La Lastra A, Fu C, Hogg GD, Kingston NL, Breden MA, Dodhiawala PB, Zhou DC, Lander VE, James CA, Ding L, Lim KH, Fields RC, Hawkins WG, Weber JD, Zhao G, DeNardo DG. Zuo C, et al. Among authors: lander ve. J Exp Med. 2023 Jun 5;220(6):e20212062. doi: 10.1084/jem.20212062. Epub 2023 Mar 23. J Exp Med. 2023. PMID: 36951731 Free PMC article.
Systemic Alterations in Type-2 Conventional Dendritic Cells Lead to Impaired Tumor Immunity in Pancreatic Cancer.
James CA, Baer JM, Zou C, Panni UY, Knolhoff BL, Hogg GD, Kingston NL, Kang LI, Lander VE, Luo J, Tao Y, Watson MA, Aft R, Fields RC, Hawkins WG, DeNardo DG. James CA, et al. Among authors: lander ve. Cancer Immunol Res. 2023 Aug 3;11(8):1055-1067. doi: 10.1158/2326-6066.CIR-21-0946. Cancer Immunol Res. 2023. PMID: 37229629 Free PMC article.
Context-dependent activation of STING-interferon signaling by CD11b agonists enhances anti-tumor immunity.
Liu X, Hogg GD, Zuo C, Borcherding NC, Baer JM, Lander VE, Kang LI, Knolhoff BL, Ahmad F, Osterhout RE, Galkin AV, Bruey JM, Carter LL, Mpoy C, Vij KR, Fields RC, Schwarz JK, Park H, Gupta V, DeNardo DG. Liu X, et al. Among authors: lander ve. Cancer Cell. 2023 Jun 12;41(6):1073-1090.e12. doi: 10.1016/j.ccell.2023.04.018. Epub 2023 May 25. Cancer Cell. 2023. PMID: 37236195