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Neurons burdened by DNA double-strand breaks incite microglia activation through antiviral-like signaling in neurodegeneration.
Sci Adv. 2022 Sep 30;8(39):eabo4662. doi: 10.1126/sciadv.abo4662. Epub 2022 Sep 28.
Sci Adv. 2022.
PMID: 36170369
Free PMC article.
Lipid accumulation induced by APOE4 impairs microglial surveillance of neuronal-network activity.
Victor MB, Leary N, Luna X, Meharena HS, Scannail AN, Bozzelli PL, Samaan G, Murdock MH, von Maydell D, Effenberger AH, Cerit O, Wen HL, Liu L, Welch G, Bonner M, Tsai LH.
Victor MB, et al.
Cell Stem Cell. 2022 Aug 4;29(8):1197-1212.e8. doi: 10.1016/j.stem.2022.07.005.
Cell Stem Cell. 2022.
PMID: 35931030
Free PMC article.
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Single-cell atlas reveals correlates of high cognitive function, dementia, and resilience to Alzheimer's disease pathology.
Mathys H, Peng Z, Boix CA, Victor MB, Leary N, Babu S, Abdelhady G, Jiang X, Ng AP, Ghafari K, Kunisky AK, Mantero J, Galani K, Lohia VN, Fortier GE, Lotfi Y, Ivey J, Brown HP, Patel PR, Chakraborty N, Beaudway JI, Imhoff EJ, Keeler CF, McChesney MM, Patel HH, Patel SP, Thai MT, Bennett DA, Kellis M, Tsai LH.
Mathys H, et al.
Cell. 2023 Sep 28;186(20):4365-4385.e27. doi: 10.1016/j.cell.2023.08.039.
Cell. 2023.
PMID: 37774677
Free article.
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Human microglial state dynamics in Alzheimer's disease progression.
Sun N, Victor MB, Park YP, Xiong X, Scannail AN, Leary N, Prosper S, Viswanathan S, Luna X, Boix CA, James BT, Tanigawa Y, Galani K, Mathys H, Jiang X, Ng AP, Bennett DA, Tsai LH, Kellis M.
Sun N, et al.
Cell. 2023 Sep 28;186(20):4386-4403.e29. doi: 10.1016/j.cell.2023.08.037.
Cell. 2023.
PMID: 37774678
Free article.
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Multisensory gamma stimulation promotes glymphatic clearance of amyloid.
Murdock MH, Yang CY, Sun N, Pao PC, Blanco-Duque C, Kahn MC, Kim T, Lavoie NS, Victor MB, Islam MR, Galiana F, Leary N, Wang S, Bubnys A, Ma E, Akay LA, Sneve M, Qian Y, Lai C, McCarthy MM, Kopell N, Kellis M, Piatkevich KD, Boyden ES, Tsai LH.
Murdock MH, et al. Among authors: leary n.
Nature. 2024 Mar;627(8002):149-156. doi: 10.1038/s41586-024-07132-6. Epub 2024 Feb 28.
Nature. 2024.
PMID: 38418876
Free PMC article.
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