Freeman GJ - Search Results

1

PD-1 combination therapy with IL-2 modifies CD8⁺ T cell exhaustion program.

Hashimoto M, Araki K, Cardenas MA, Li P, Jadhav RR, Kissick HT, Hudson WH, McGuire DJ, Obeng RC, Wieland A, Lee J, McManus DT, Ross JL, Im SJ, Lee J, Lin JX, Hu B, West EE, Scharer CD, Freeman GJ, Sharpe AH, Ramalingam SS, Pellerin A, Teichgräber V, Greenleaf WJ, Klein C, Goronzy JJ, Umaña P, Leonard WJ, Smith KA, Ahmed R. Hashimoto M, et al. Among authors: freeman gj. Nature. 2022 Oct;610(7930):173-181. doi: 10.1038/s41586-022-05257-0. Epub 2022 Sep 28. Nature. 2022. PMID: 36171288 Free PMC article.

2

Differential expression of alternate mB7-2 transcripts.

Borriello F, Oliveros J, Freeman GJ, Nadler LM, Sharpe AH. Borriello F, et al. Among authors: freeman gj. J Immunol. 1995 Dec 15;155(12):5490-7. J Immunol. 1995. PMID: 7499829

3

Characterization of the murine B7-1 genomic locus reveals an additional exon encoding an alternative cytoplasmic domain and a chromosomal location of chromosome 16, band B5.

Borriello F, Freeman GJ, Edelhoff S, Disteche CM, Nadler LM, Sharpe AH. Borriello F, et al. Among authors: freeman gj. J Immunol. 1994 Dec 1;153(11):5038-48. J Immunol. 1994. PMID: 7525722

4

A negative regulatory function of B7 revealed in B7-1 transgenic mice.

Sethna MP, van Parijs L, Sharpe AH, Abbas AK, Freeman GJ. Sethna MP, et al. Among authors: freeman gj. Immunity. 1994 Aug;1(5):415-21. doi: 10.1016/1074-7613(94)90072-8. Immunity. 1994. PMID: 7533646

5

Mouse inducible costimulatory molecule (ICOS) expression is enhanced by CD28 costimulation and regulates differentiation of CD4+ T cells.

McAdam AJ, Chang TT, Lumelsky AE, Greenfield EA, Boussiotis VA, Duke-Cohan JS, Chernova T, Malenkovich N, Jabs C, Kuchroo VK, Ling V, Collins M, Sharpe AH, Freeman GJ. McAdam AJ, et al. Among authors: freeman gj. J Immunol. 2000 Nov 1;165(9):5035-40. doi: 10.4049/jimmunol.165.9.5035. J Immunol. 2000. PMID: 11046032

6

Intercellular adhesion molecule 1 is critical for activation of CD28-deficient T cells.

Gaglia JL, Greenfield EA, Mattoo A, Sharpe AH, Freeman GJ, Kuchroo VK. Gaglia JL, et al. Among authors: freeman gj. J Immunol. 2000 Dec 1;165(11):6091-8. doi: 10.4049/jimmunol.165.11.6091. J Immunol. 2000. PMID: 11086041

7

PD-L2 is a second ligand for PD-1 and inhibits T cell activation.

Latchman Y, Wood CR, Chernova T, Chaudhary D, Borde M, Chernova I, Iwai Y, Long AJ, Brown JA, Nunes R, Greenfield EA, Bourque K, Boussiotis VA, Carter LL, Carreno BM, Malenkovich N, Nishimura H, Okazaki T, Honjo T, Sharpe AH, Freeman GJ. Latchman Y, et al. Among authors: freeman gj. Nat Immunol. 2001 Mar;2(3):261-8. doi: 10.1038/85330. Nat Immunol. 2001. PMID: 11224527

8

B7-dependent T-cell costimulation in mice lacking CD28 and CTLA4.

Mandelbrot DA, Oosterwegel MA, Shimizu K, Yamada A, Freeman GJ, Mitchell RN, Sayegh MH, Sharpe AH. Mandelbrot DA, et al. Among authors: freeman gj. J Clin Invest. 2001 Apr;107(7):881-7. doi: 10.1172/JCI11710. J Clin Invest. 2001. PMID: 11285307 Free PMC article.

9

ICOS is critical for CD40-mediated antibody class switching.

McAdam AJ, Greenwald RJ, Levin MA, Chernova T, Malenkovich N, Ling V, Freeman GJ, Sharpe AH. McAdam AJ, et al. Among authors: freeman gj. Nature. 2001 Jan 4;409(6816):102-5. doi: 10.1038/35051107. Nature. 2001. PMID: 11343122

10

PD-1:PD-L inhibitory pathway affects both CD4(+) and CD8(+) T cells and is overcome by IL-2.

Carter L, Fouser LA, Jussif J, Fitz L, Deng B, Wood CR, Collins M, Honjo T, Freeman GJ, Carreno BM. Carter L, et al. Among authors: freeman gj. Eur J Immunol. 2002 Mar;32(3):634-43. doi: 10.1002/1521-4141(200203)32:3<634::AID-IMMU634>3.0.CO;2-9. Eur J Immunol. 2002. PMID: 11857337 Free article.

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