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PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program.
Hashimoto M, Araki K, Cardenas MA, Li P, Jadhav RR, Kissick HT, Hudson WH, McGuire DJ, Obeng RC, Wieland A, Lee J, McManus DT, Ross JL, Im SJ, Lee J, Lin JX, Hu B, West EE, Scharer CD, Freeman GJ, Sharpe AH, Ramalingam SS, Pellerin A, Teichgräber V, Greenleaf WJ, Klein C, Goronzy JJ, Umaña P, Leonard WJ, Smith KA, Ahmed R. Hashimoto M, et al. Among authors: goronzy jj. Nature. 2022 Oct;610(7930):173-181. doi: 10.1038/s41586-022-05257-0. Epub 2022 Sep 28. Nature. 2022. PMID: 36171288 Free PMC article.
T-cell-targeted therapies in rheumatoid arthritis.
Weyand CM, Goronzy JJ. Weyand CM, et al. Among authors: goronzy jj. Nat Clin Pract Rheumatol. 2006 Apr;2(4):201-10. doi: 10.1038/ncprheum0142. Nat Clin Pract Rheumatol. 2006. PMID: 16932686 Review.
Epigenomics of human CD8 T cell differentiation and aging.
Moskowitz DM, Zhang DW, Hu B, Le Saux S, Yanes RE, Ye Z, Buenrostro JD, Weyand CM, Greenleaf WJ, Goronzy JJ. Moskowitz DM, et al. Among authors: goronzy jj. Sci Immunol. 2017 Feb;2(8):eaag0192. doi: 10.1126/sciimmunol.aag0192. Epub 2017 Feb 17. Sci Immunol. 2017. PMID: 28439570 Free PMC article.
Immune Checkpoint Function of CD85j in CD8 T Cell Differentiation and Aging.
Gustafson CE, Qi Q, Hutter-Saunders J, Gupta S, Jadhav R, Newell E, Maecker H, Weyand CM, Goronzy JJ. Gustafson CE, et al. Among authors: goronzy jj. Front Immunol. 2017 Jun 14;8:692. doi: 10.3389/fimmu.2017.00692. eCollection 2017. Front Immunol. 2017. PMID: 28659925 Free PMC article.
Origin and differentiation of human memory CD8 T cells after vaccination.
Akondy RS, Fitch M, Edupuganti S, Yang S, Kissick HT, Li KW, Youngblood BA, Abdelsamed HA, McGuire DJ, Cohen KW, Alexe G, Nagar S, McCausland MM, Gupta S, Tata P, Haining WN, McElrath MJ, Zhang D, Hu B, Greenleaf WJ, Goronzy JJ, Mulligan MJ, Hellerstein M, Ahmed R. Akondy RS, et al. Among authors: goronzy jj. Nature. 2017 Dec 21;552(7685):362-367. doi: 10.1038/nature24633. Epub 2017 Dec 13. Nature. 2017. PMID: 29236685 Free PMC article.
Epigenetics of T cell aging.
Goronzy JJ, Hu B, Kim C, Jadhav RR, Weyand CM. Goronzy JJ, et al. J Leukoc Biol. 2018 Oct;104(4):691-699. doi: 10.1002/JLB.1RI0418-160R. Epub 2018 Jun 27. J Leukoc Biol. 2018. PMID: 29947427 Free PMC article. Review.
Regulation of miR-181a expression in T cell aging.
Ye Z, Li G, Kim C, Hu B, Jadhav RR, Weyand CM, Goronzy JJ. Ye Z, et al. Among authors: goronzy jj. Nat Commun. 2018 Aug 3;9(1):3060. doi: 10.1038/s41467-018-05552-3. Nat Commun. 2018. PMID: 30076309 Free PMC article.
422 results