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A noncoding single-nucleotide polymorphism at 8q24 drives IDH1-mutant glioma formation.
Yanchus C, Drucker KL, Kollmeyer TM, Tsai R, Winick-Ng W, Liang M, Malik A, Pawling J, De Lorenzo SB, Ali A, Decker PA, Kosel ML, Panda A, Al-Zahrani KN, Jiang L, Browning JWL, Lowden C, Geuenich M, Hernandez JJ, Gosio JT, Ahmed M, Loganathan SK, Berman J, Trcka D, Michealraj KA, Fortin J, Carson B, Hollingsworth EW, Jacinto S, Mazrooei P, Zhou L, Elia A, Lupien M, He HH, Murphy DJ, Wang L, Abyzov A, Dennis JW, Maass PG, Campbell K, Wilson MD, Lachance DH, Wrensch M, Wiencke J, Mak T, Pennacchio LA, Dickel DE, Visel A, Wrana J, Taylor MD, Zadeh G, Dirks P, Eckel-Passow JE, Attisano L, Pombo A, Ida CM, Kvon EZ, Jenkins RB, Schramek D. Yanchus C, et al. Among authors: murphy dj. Science. 2022 Oct 7;378(6615):68-78. doi: 10.1126/science.abj2890. Epub 2022 Oct 6. Science. 2022. PMID: 36201590 Free PMC article.
TFEB links MYC signaling to epigenetic control of myeloid differentiation and acute myeloid leukemia.
Yun S, Vincelette ND, Yu X, Watson GW, Fernandez MR, Yang C, Hitosugi T, Cheng CH, Freischel AR, Zhang L, Li W, Hou H, Schaub FX, Vedder AR, Cen L, McGraw KL, Moon J, Murphy DJ, Ballabio A, Kaufmann SH, Berglund AE, Cleveland JL. Yun S, et al. Among authors: murphy dj. Blood Cancer Discov. 2021 Mar;2(2):162-185. doi: 10.1158/2643-3230.BCD-20-0029. Blood Cancer Discov. 2021. PMID: 33860275 Free PMC article.
The ERBB network facilitates KRAS-driven lung tumorigenesis.
Kruspig B, Monteverde T, Neidler S, Hock A, Kerr E, Nixon C, Clark W, Hedley A, Laing S, Coffelt SB, Le Quesne J, Dick C, Vousden KH, Martins CP, Murphy DJ. Kruspig B, et al. Among authors: murphy dj. Sci Transl Med. 2018 Jun 20;10(446):eaao2565. doi: 10.1126/scitranslmed.aao2565. Sci Transl Med. 2018. PMID: 29925636 Free PMC article.
Repression of the Type I Interferon Pathway Underlies MYC- and KRAS-Dependent Evasion of NK and B Cells in Pancreatic Ductal Adenocarcinoma.
Muthalagu N, Monteverde T, Raffo-Iraolagoitia X, Wiesheu R, Whyte D, Hedley A, Laing S, Kruspig B, Upstill-Goddard R, Shaw R, Neidler S, Rink C, Karim SA, Gyuraszova K, Nixon C, Clark W, Biankin AV, Carlin LM, Coffelt SB, Sansom OJ, Morton JP, Murphy DJ. Muthalagu N, et al. Among authors: murphy dj. Cancer Discov. 2020 Jun;10(6):872-887. doi: 10.1158/2159-8290.CD-19-0620. Epub 2020 Mar 21. Cancer Discov. 2020. PMID: 32200350 Free PMC article.
BIM's up first.
Murphy DJ, Muthalagu N. Murphy DJ, et al. Mol Cell Oncol. 2014 Dec 1;2(2):e975083. doi: 10.4161/23723556.2014.975083. eCollection 2015 Apr-Jun. Mol Cell Oncol. 2014. PMID: 27308426 Free PMC article.
Id2 is dispensable for Myc-induced epidermal neoplasia.
Murphy DJ, Swigart LB, Israel MA, Evan GI. Murphy DJ, et al. Mol Cell Biol. 2004 Mar;24(5):2083-90. doi: 10.1128/MCB.24.5.2083-2090.2004. Mol Cell Biol. 2004. PMID: 14966287 Free PMC article.
Distinct thresholds govern Myc's biological output in vivo.
Murphy DJ, Junttila MR, Pouyet L, Karnezis A, Shchors K, Bui DA, Brown-Swigart L, Johnson L, Evan GI. Murphy DJ, et al. Cancer Cell. 2008 Dec 9;14(6):447-57. doi: 10.1016/j.ccr.2008.10.018. Cancer Cell. 2008. PMID: 19061836 Free PMC article.
727 results