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A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants.
Han Y, Tan L, Zhou T, Yang L, Carrau L, Lacko LA, Saeed M, Zhu J, Zhao Z, Nilsson-Payant BE, Lira Neto FT, Cahir C, Giani AM, Chai JC, Li Y, Dong X, Moroziewicz D; NYSCF Global Stem Cell Array Team; Paull D, Zhang T, Koo S, Tan C, Danziger R, Ba Q, Feng L, Chen Z, Zhong A, Wise GJ, Xiang JZ, Wang H, Schwartz RE, tenOever BR, Noggle SA, Rice CM, Qi Q, Evans T, Chen S. Han Y, et al. Among authors: chen z, chen s. Cell Stem Cell. 2022 Oct 6;29(10):1475-1490.e6. doi: 10.1016/j.stem.2022.09.008. Cell Stem Cell. 2022. PMID: 36206731 Free PMC article.
An Immuno-Cardiac Model for Macrophage-Mediated Inflammation in COVID-19 Hearts.
Yang L, Han Y, Jaffré F, Nilsson-Payant BE, Bram Y, Wang P, Zhu J, Zhang T, Redmond D, Houghton S, Uhl S, Borczuk A, Huang Y, Richardson C, Chandar V, Acklin JA, Lim JK, Chen Z, Xiang J, Ho DD, tenOever BR, Schwartz RE, Evans T, Chen S. Yang L, et al. Among authors: chen z, chen s. Circ Res. 2021 Jun 25;129(1):33-46. doi: 10.1161/CIRCRESAHA.121.319060. Epub 2021 Apr 15. Circ Res. 2021. PMID: 33853355 Free PMC article.
SARS-CoV-2 Infection Induces Ferroptosis of Sinoatrial Node Pacemaker Cells.
Han Y, Zhu J, Yang L, Nilsson-Payant BE, Hurtado R, Lacko LA, Sun X, Gade AR, Higgins CA, Sisso WJ, Dong X, Wang M, Chen Z, Ho DD, Pitt GS, Schwartz RE, tenOever BR, Evans T, Chen S. Han Y, et al. Among authors: chen z, chen s. Circ Res. 2022 Apr;130(7):963-977. doi: 10.1161/CIRCRESAHA.121.320518. Epub 2022 Mar 8. Circ Res. 2022. PMID: 35255712 Free PMC article.
Bcl-xL is translocated to the nucleus via CtBP2 to epigenetically promote metastasis.
Zhang T, Li S, Tan YA, Na JH, Chen Z, Damle P, Chen X, Choi S, Mishra B, Wang D, Grossman SR, Jiang X, Li Y, Chen YT, Xiang JZ, Du YN. Zhang T, et al. Among authors: chen z, chen x, chen yt. bioRxiv [Preprint]. 2023 Apr 28:2023.04.26.538373. doi: 10.1101/2023.04.26.538373. bioRxiv. 2023. PMID: 37163116 Free PMC article. Preprint.
Isogenic human trophectoderm cells demonstrate the role of NDUFA4 and associated variants in ZIKV infection.
Yang L, Han Y, Zhou T, Lacko LA, Saeed M, Tan C, Danziger R, Zhu J, Zhao Z, Cahir C, Giani AM, Li Y, Dong X, Moroziewicz D; NYSCF Global Stem Cell Array® Team; Paull D, Chen Z, Zhong A, Noggle SA, Rice CM, Qi Q, Evans T, Chen S. Yang L, et al. Among authors: chen z, chen s. iScience. 2023 May 29;26(7):107001. doi: 10.1016/j.isci.2023.107001. eCollection 2023 Jul 21. iScience. 2023. PMID: 37534130 Free PMC article.
Checkpoint kinase 2 controls insulin secretion and glucose homeostasis.
Chong ACN, Vandana JJ, Jeng G, Li G, Meng Z, Duan X, Zhang T, Qiu Y, Duran-Struuck R, Coker K, Wang W, Li Y, Min Z, Zuo X, de Silva N, Chen Z, Naji A, Hao M, Liu C, Chen S. Chong ACN, et al. Among authors: chen z, chen s. Nat Chem Biol. 2024 May;20(5):566-576. doi: 10.1038/s41589-023-01466-4. Epub 2023 Nov 9. Nat Chem Biol. 2024. PMID: 37945898 Free PMC article.
Low-dose carbon monoxide suppresses metastatic progression of disseminated cancer cells.
Zhang T, Zhang G, Chen X, Chen Z, Tan AY, Lin A, Zhang C, Torres LK, Bajrami S, Zhang T, Zhang G, Xiang JZ, Hissong EM, Chen YT, Li Y, Du YN. Zhang T, et al. Among authors: chen z, chen x, chen yt. Cancer Lett. 2022 Oct 10;546:215831. doi: 10.1016/j.canlet.2022.215831. Epub 2022 Jul 19. Cancer Lett. 2022. PMID: 35868533
Whole-Exome Sequencing of Metastatic Cancer and Biomarkers of Treatment Response.
Beltran H, Eng K, Mosquera JM, Sigaras A, Romanel A, Rennert H, Kossai M, Pauli C, Faltas B, Fontugne J, Park K, Banfelder J, Prandi D, Madhukar N, Zhang T, Padilla J, Greco N, McNary TJ, Herrscher E, Wilkes D, MacDonald TY, Xue H, Vacic V, Emde AK, Oschwald D, Tan AY, Chen Z, Collins C, Gleave ME, Wang Y, Chakravarty D, Schiffman M, Kim R, Campagne F, Robinson BD, Nanus DM, Tagawa ST, Xiang JZ, Smogorzewska A, Demichelis F, Rickman DS, Sboner A, Elemento O, Rubin MA. Beltran H, et al. Among authors: chen z. JAMA Oncol. 2015 Jul;1(4):466-74. doi: 10.1001/jamaoncol.2015.1313. JAMA Oncol. 2015. PMID: 26181256 Free PMC article.
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