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Identification and characterization of a novel SNAT2 (SLC38A2) inhibitor reveals synergy with glucose transport inhibition in cancer cells.
Front Pharmacol. 2022 Sep 21;13:963066. doi: 10.3389/fphar.2022.963066. eCollection 2022.
Front Pharmacol. 2022.
PMID: 36210829
Free PMC article.
Ablation of the ASCT2 (SLC1A5) gene encoding a neutral amino acid transporter reveals transporter plasticity and redundancy in cancer cells.
Bröer A, Gauthier-Coles G, Rahimi F, van Geldermalsen M, Dorsch D, Wegener A, Holst J, Bröer S.
Bröer A, et al. Among authors: gauthier coles g.
J Biol Chem. 2019 Mar 15;294(11):4012-4026. doi: 10.1074/jbc.RA118.006378. Epub 2019 Jan 11.
J Biol Chem. 2019.
PMID: 30635397
Free PMC article.
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A GC-MS/Single-Cell Method to Evaluate Membrane Transporter Substrate Specificity and Signaling.
Fairweather SJ, Okada S, Gauthier-Coles G, Javed K, Bröer A, Bröer S.
Fairweather SJ, et al. Among authors: gauthier coles g.
Front Mol Biosci. 2021 Apr 13;8:646574. doi: 10.3389/fmolb.2021.646574. eCollection 2021.
Front Mol Biosci. 2021.
PMID: 33928121
Free PMC article.
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Quantitative modelling of amino acid transport and homeostasis in mammalian cells.
Gauthier-Coles G, Vennitti J, Zhang Z, Comb WC, Xing S, Javed K, Bröer A, Bröer S.
Gauthier-Coles G, et al.
Nat Commun. 2021 Sep 6;12(1):5282. doi: 10.1038/s41467-021-25563-x.
Nat Commun. 2021.
PMID: 34489418
Free PMC article.
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Amino Acid Homeostasis in Mammalian Cells with a Focus on Amino Acid Transport.
Bröer S, Gauthier-Coles G.
Bröer S, et al. Among authors: gauthier coles g.
J Nutr. 2022 Jan 11;152(1):16-28. doi: 10.1093/jn/nxab342.
J Nutr. 2022.
PMID: 34718668
Free PMC article.
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Impact of Inhibition of Glutamine and Alanine Transport on Cerebellar Glial and Neuronal Metabolism.
Das A, Gauthier-Coles G, Bröer S, Rae CD.
Das A, et al. Among authors: gauthier coles g.
Biomolecules. 2022 Aug 27;12(9):1189. doi: 10.3390/biom12091189.
Biomolecules. 2022.
PMID: 36139028
Free PMC article.
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Do Amino Acid Antiporters Have Asymmetric Substrate Specificity?
Gauthier-Coles G, Fairweather SJ, Bröer A, Bröer S.
Gauthier-Coles G, et al.
Biomolecules. 2023 Feb 6;13(2):301. doi: 10.3390/biom13020301.
Biomolecules. 2023.
PMID: 36830670
Free PMC article.
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Inhibition of GCN2 Reveals Synergy with Cell-Cycle Regulation and Proteostasis.
Gauthier-Coles G, Rahimi F, Bröer A, Bröer S.
Gauthier-Coles G, et al.
Metabolites. 2023 Oct 9;13(10):1064. doi: 10.3390/metabo13101064.
Metabolites. 2023.
PMID: 37887389
Free PMC article.
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