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Blockade of TGF-β signaling with novel synthetic antibodies limits immune exclusion and improves chemotherapy response in metastatic ovarian cancer models.
Newsted D, Banerjee S, Watt K, Nersesian S, Truesdell P, Blazer LL, Cardarelli L, Adams JJ, Sidhu SS, Craig AW. Newsted D, et al. Among authors: sidhu ss. Oncoimmunology. 2018 Nov 20;8(2):e1539613. doi: 10.1080/2162402X.2018.1539613. eCollection 2019. Oncoimmunology. 2018. PMID: 30713798 Free PMC article.
Structure-guided design fine-tunes pharmacokinetics, tolerability, and antitumor profile of multispecific frizzled antibodies.
Raman S, Beilschmidt M, To M, Lin K, Lui F, Jmeian Y, Ng M, Fernandez M, Fu Y, Mascall K, Duque A, Wang X, Pan G, Angers S, Moffat J, Sidhu SS, Magram J, Sinclair AM, Fransson J, Julien JP. Raman S, et al. Among authors: sidhu ss. Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):6812-6817. doi: 10.1073/pnas.1817246116. Epub 2019 Mar 20. Proc Natl Acad Sci U S A. 2019. PMID: 30894493 Free PMC article.
462 results