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LRRC15 inhibits SARS-CoV-2 cellular entry in trans.
Song J, Chow RD, Peña-Hernández MA, Zhang L, Loeb SA, So EY, Liang OD, Ren P, Chen S, Wilen CB, Lee S. Song J, et al. Among authors: liang od. PLoS Biol. 2022 Oct 13;20(10):e3001805. doi: 10.1371/journal.pbio.3001805. eCollection 2022 Oct. PLoS Biol. 2022. PMID: 36228039 Free PMC article.
Natural Killer cell activation, reduced ACE2, TMPRSS2, cytokines G-CSF, M-CSF and SARS-CoV-2-S pseudovirus infectivity by MEK inhibitor treatment of human cells.
Zhou L, Huntington K, Zhang S, Carlsen L, So EY, Parker C, Sahin I, Safran H, Kamle S, Lee CM, Lee CG, Elias JA, Campbell KS, Naik MT, Atwood WJ, Youssef E, Pachter JA, Navaraj A, Seyhan AA, Liang O, El-Deiry WS. Zhou L, et al. bioRxiv [Preprint]. 2020 Sep 2:2020.08.02.230839. doi: 10.1101/2020.08.02.230839. bioRxiv. 2020. PMID: 32793908 Free PMC article. Preprint.
MEK inhibitors reduce cellular expression of ACE2, pERK, pRb while stimulating NK-mediated cytotoxicity and attenuating inflammatory cytokines relevant to SARS-CoV-2 infection.
Zhou L, Huntington K, Zhang S, Carlsen L, So EY, Parker C, Sahin I, Safran H, Kamle S, Lee CM, Geun Lee C, A Elias J, S Campbell K, T Naik M, J Atwood W, Youssef E, A Pachter J, Navaraj A, A Seyhan A, Liang O, El-Deiry WS. Zhou L, et al. Oncotarget. 2020 Nov 17;11(46):4201-4223. doi: 10.18632/oncotarget.27799. eCollection 2020 Nov 17. Oncotarget. 2020. PMID: 33245731 Free PMC article.
Targeting RUNX1 as a novel treatment modality for pulmonary arterial hypertension.
Jeong EM, Pereira M, So EY, Wu KQ, Del Tatto M, Wen S, Dooner MS, Dubielecka PM, Reginato AM, Ventetuolo CE, Quesenberry PJ, Klinger JR, Liang OD. Jeong EM, et al. Among authors: liang od. Cardiovasc Res. 2022 Dec 29;118(16):3211-3224. doi: 10.1093/cvr/cvac001. Cardiovasc Res. 2022. PMID: 35018410 Free PMC article.
56 results