Mischel PS - Search Results

1

Targeted profiling of human extrachromosomal DNA by CRISPR-CATCH.

Hung KL, Luebeck J, Dehkordi SR, Colón CI, Li R, Wong IT, Coruh C, Dharanipragada P, Lomeli SH, Weiser NE, Moriceau G, Zhang X, Bailey C, Houlahan KE, Yang W, González RC, Swanton C, Curtis C, Jamal-Hanjani M, Henssen AG, Law JA, Greenleaf WJ, Lo RS, Mischel PS, Bafna V, Chang HY. Hung KL, et al. Among authors: mischel ps. Nat Genet. 2022 Nov;54(11):1746-1754. doi: 10.1038/s41588-022-01190-0. Epub 2022 Oct 17. Nat Genet. 2022. PMID: 36253572 Free PMC article.

2

Differential sensitivity of melanoma cell lines with BRAFV600E mutation to the specific Raf inhibitor PLX4032.

Søndergaard JN, Nazarian R, Wang Q, Guo D, Hsueh T, Mok S, Sazegar H, MacConaill LE, Barretina JG, Kehoe SM, Attar N, von Euw E, Zuckerman JE, Chmielowski B, Comin-Anduix B, Koya RC, Mischel PS, Lo RS, Ribas A. Søndergaard JN, et al. Among authors: mischel ps. J Transl Med. 2010 Apr 20;8:39. doi: 10.1186/1479-5876-8-39. J Transl Med. 2010. PMID: 20406486 Free PMC article.

3

Combination therapy with vemurafenib (PLX4032/RG7204) and metformin in melanoma cell lines with distinct driver mutations.

Niehr F, von Euw E, Attar N, Guo D, Matsunaga D, Sazegar H, Ng C, Glaspy JA, Recio JA, Lo RS, Mischel PS, Comin-Anduix B, Ribas A. Niehr F, et al. Among authors: mischel ps. J Transl Med. 2011 May 24;9:76. doi: 10.1186/1479-5876-9-76. J Transl Med. 2011. PMID: 21609436 Free PMC article.

4

Reversing melanoma cross-resistance to BRAF and MEK inhibitors by co-targeting the AKT/mTOR pathway.

Atefi M, von Euw E, Attar N, Ng C, Chu C, Guo D, Nazarian R, Chmielowski B, Glaspy JA, Comin-Anduix B, Mischel PS, Lo RS, Ribas A. Atefi M, et al. Among authors: mischel ps. PLoS One. 2011;6(12):e28973. doi: 10.1371/journal.pone.0028973. Epub 2011 Dec 14. PLoS One. 2011. PMID: 22194965 Free PMC article.

5

Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death.

Graham NA, Tahmasian M, Kohli B, Komisopoulou E, Zhu M, Vivanco I, Teitell MA, Wu H, Ribas A, Lo RS, Mellinghoff IK, Mischel PS, Graeber TG. Graham NA, et al. Among authors: mischel ps. Mol Syst Biol. 2012 Jun 26;8:589. doi: 10.1038/msb.2012.20. Mol Syst Biol. 2012. PMID: 22735335 Free PMC article.

6

Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity.

Turner KM, Deshpande V, Beyter D, Koga T, Rusert J, Lee C, Li B, Arden K, Ren B, Nathanson DA, Kornblum HI, Taylor MD, Kaushal S, Cavenee WK, Wechsler-Reya R, Furnari FB, Vandenberg SR, Rao PN, Wahl GM, Bafna V, Mischel PS. Turner KM, et al. Among authors: mischel ps. Nature. 2017 Mar 2;543(7643):122-125. doi: 10.1038/nature21356. Epub 2017 Feb 8. Nature. 2017. PMID: 28178237 Free PMC article.

7

ViFi: accurate detection of viral integration and mRNA fusion reveals indiscriminate and unregulated transcription in proximal genomic regions in cervical cancer.

Nguyen ND, Deshpande V, Luebeck J, Mischel PS, Bafna V. Nguyen ND, et al. Among authors: mischel ps. Nucleic Acids Res. 2018 Apr 20;46(7):3309-3325. doi: 10.1093/nar/gky180. Nucleic Acids Res. 2018. PMID: 29579309 Free PMC article.

8

Exploring the landscape of focal amplifications in cancer using AmpliconArchitect.

Deshpande V, Luebeck J, Nguyen ND, Bakhtiari M, Turner KM, Schwab R, Carter H, Mischel PS, Bafna V. Deshpande V, et al. Among authors: mischel ps. Nat Commun. 2019 Jan 23;10(1):392. doi: 10.1038/s41467-018-08200-y. Nat Commun. 2019. PMID: 30674876 Free PMC article.

9

Extrachromosomal oncogene amplification in tumour pathogenesis and evolution.

Verhaak RGW, Bafna V, Mischel PS. Verhaak RGW, et al. Among authors: mischel ps. Nat Rev Cancer. 2019 May;19(5):283-288. doi: 10.1038/s41568-019-0128-6. Nat Rev Cancer. 2019. PMID: 30872802 Free PMC article. Review.

10

NAD metabolic dependency in cancer is shaped by gene amplification and enhancer remodelling.

Chowdhry S, Zanca C, Rajkumar U, Koga T, Diao Y, Raviram R, Liu F, Turner K, Yang H, Brunk E, Bi J, Furnari F, Bafna V, Ren B, Mischel PS. Chowdhry S, et al. Among authors: mischel ps. Nature. 2019 May;569(7757):570-575. doi: 10.1038/s41586-019-1150-2. Epub 2019 Apr 24. Nature. 2019. PMID: 31019297 Free PMC article.

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