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An arrayed genome-wide perturbation screen identifies the ribonucleoprotein Hnrnpk as rate-limiting for prion propagation.
EMBO J. 2022 Dec 1;41(23):e112338. doi: 10.15252/embj.2022112338. Epub 2022 Oct 18.
EMBO J. 2022.
PMID: 36254605
Free PMC article.
Genome-wide identification of microRNAs regulating the human prion protein.
Pease D, Scheckel C, Schaper E, Eckhardt V, Emmenegger M, Xenarios I, Aguzzi A.
Pease D, et al.
Brain Pathol. 2019 Mar;29(2):232-244. doi: 10.1111/bpa.12679. Epub 2018 Dec 21.
Brain Pathol. 2019.
PMID: 30451334
Free PMC article.
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Novel regulators of PrPC biosynthesis revealed by genome-wide RNA interference.
Heinzer D, Avar M, Pease DP, Dhingra A, Yin JA, Schaper E, Doğançay B, Emmenegger M, Spinelli A, Maggi K, Chincisan A, Mead S, Hornemann S, Heutink P, Aguzzi A.
Heinzer D, et al. Among authors: pease dp.
PLoS Pathog. 2021 Oct 27;17(10):e1010013. doi: 10.1371/journal.ppat.1010013. eCollection 2021 Oct.
PLoS Pathog. 2021.
PMID: 34705895
Free PMC article.
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An integrated genomic approach to dissect the genetic landscape regulating the cell-to-cell transfer of α-synuclein.
Kara E, Crimi A, Wiedmer A, Emmenegger M, Manzoni C, Bandres-Ciga S, D'Sa K, Reynolds RH, Botía JA, Losa M, Lysenko V, Carta M, Heinzer D, Avar M, Chincisan A, Blauwendraat C, García-Ruiz S, Pease D, Mottier L, Carrella A, Beck-Schneider D, Magalhães AD, Aemisegger C, Theocharides APA, Fan Z, Marks JD, Hopp SC, Abramov AY, Lewis PA, Ryten M, Hardy J, Hyman BT, Aguzzi A.
Kara E, et al.
Cell Rep. 2021 Jun 8;35(10):109189. doi: 10.1016/j.celrep.2021.109189.
Cell Rep. 2021.
PMID: 34107263
Free PMC article.
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Somatic copy number gains of α-synuclein (SNCA) in Parkinson's disease and multiple system atrophy brains.
Mokretar K, Pease D, Taanman JW, Soenmez A, Ejaz A, Lashley T, Ling H, Gentleman S, Houlden H, Holton JL, Schapira AHV, Nacheva E, Proukakis C.
Mokretar K, et al.
Brain. 2018 Aug 1;141(8):2419-2431. doi: 10.1093/brain/awy157.
Brain. 2018.
PMID: 29917054
Free article.
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