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SMG8/SMG9 Heterodimer Loss Modulates SMG1 Kinase to Drive ATR Inhibitor Resistance.
Llorca-Cardenosa MJ, Aronson LI, Krastev DB, Nieminuszczy J, Alexander J, Song F, Dylewska M, Broderick R, Brough R, Zimmermann A, Zenke FT, Gurel B, Riisnaes R, Ferreira A, Roumeliotis T, Choudhary J, Pettitt SJ, de Bono J, Cervantes A, Haider S, Niedzwiedz W, Lord CJ, Chong IY. Llorca-Cardenosa MJ, et al. Among authors: niedzwiedz w. Cancer Res. 2022 Nov 2;82(21):3962-3973. doi: 10.1158/0008-5472.CAN-21-4339. Cancer Res. 2022. PMID: 36273494 Free PMC article.
The DNA fibre technique - tracking helicases at work.
Nieminuszczy J, Schwab RA, Niedzwiedz W. Nieminuszczy J, et al. Among authors: niedzwiedz w. Methods. 2016 Oct 1;108:92-8. doi: 10.1016/j.ymeth.2016.04.019. Epub 2016 Apr 18. Methods. 2016. PMID: 27102626 Free article. Review.
EXD2 - a new player joins the DSB resection team.
Nieminuszczy J, Broderick R, Niedzwiedz W. Nieminuszczy J, et al. Among authors: niedzwiedz w. Cell Cycle. 2016 Jun 17;15(12):1519-20. doi: 10.1080/15384101.2016.1161997. Epub 2016 May 31. Cell Cycle. 2016. PMID: 27247051 Free PMC article. No abstract available.
ATR Is a Therapeutic Target in Synovial Sarcoma.
Jones SE, Fleuren EDG, Frankum J, Konde A, Williamson CT, Krastev DB, Pemberton HN, Campbell J, Gulati A, Elliott R, Menon M, Selfe JL, Brough R, Pettitt SJ, Niedzwiedz W, van der Graaf WTA, Shipley J, Ashworth A, Lord CJ. Jones SE, et al. Among authors: niedzwiedz w. Cancer Res. 2017 Dec 15;77(24):7014-7026. doi: 10.1158/0008-5472.CAN-17-2056. Epub 2017 Oct 16. Cancer Res. 2017. PMID: 29038346 Free PMC article.
EXD2 Protects Stressed Replication Forks and Is Required for Cell Viability in the Absence of BRCA1/2.
Nieminuszczy J, Broderick R, Bellani MA, Smethurst E, Schwab RA, Cherdyntseva V, Evmorfopoulou T, Lin YL, Minczuk M, Pasero P, Gagos S, Seidman MM, Niedzwiedz W. Nieminuszczy J, et al. Among authors: niedzwiedz w. Mol Cell. 2019 Aug 8;75(3):605-619.e6. doi: 10.1016/j.molcel.2019.05.026. Epub 2019 Jun 26. Mol Cell. 2019. PMID: 31255466 Free PMC article.
Actin nucleators safeguard replication forks by limiting nascent strand degradation.
Nieminuszczy J, Martin PR, Broderick R, Krwawicz J, Kanellou A, Mocanu C, Bousgouni V, Smith C, Wen KK, Woodward BL, Bakal C, Shackley F, Aguilera A, Stewart GS, Vyas YM, Niedzwiedz W. Nieminuszczy J, et al. Among authors: niedzwiedz w. Nucleic Acids Res. 2023 Jul 7;51(12):6337-6354. doi: 10.1093/nar/gkad369. Nucleic Acids Res. 2023. PMID: 37224534 Free PMC article.
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