Brandsma AM - Search Results

1

Targeting the high affinity receptor, FcγRI, in autoimmune disease, neuropathy, and cancer.

Holtrop T, Budding K, Brandsma AM, Leusen JHW. Holtrop T, et al. Among authors: brandsma am. Immunother Adv. 2022 May 28;2(1):ltac011. doi: 10.1093/immadv/ltac011. eCollection 2022. Immunother Adv. 2022. PMID: 36284837 Free PMC article. Review.

2

Anti-tumor activity of human IgG1 anti-gp75 TA99 mAb against B16F10 melanoma in human FcgammaRI transgenic mice.

Boross P, Jansen JH, van Tetering G, Nederend M, Brandsma A, Meyer S, Torfs E, van den Ham HJ, Meulenbroek L, de Haij S, Leusen JH. Boross P, et al. Immunol Lett. 2014 Aug;160(2):151-7. doi: 10.1016/j.imlet.2014.02.005. Epub 2014 Mar 5. Immunol Lett. 2014. PMID: 24613852

3

Simultaneous Targeting of FcγRs and FcαRI Enhances Tumor Cell Killing.

Brandsma AM, Ten Broeke T, Nederend M, Meulenbroek LA, van Tetering G, Meyer S, Jansen JH, Beltrán Buitrago MA, Nagelkerke SQ, Németh I, Ubink R, Rouwendal G, Lohse S, Valerius T, Leusen JH, Boross P. Brandsma AM, et al. Cancer Immunol Res. 2015 Dec;3(12):1316-24. doi: 10.1158/2326-6066.CIR-15-0099-T. Epub 2015 Sep 25. Cancer Immunol Res. 2015. PMID: 26407589

4

Fc receptor inside-out signaling and possible impact on antibody therapy.

Brandsma AM, Jacobino SR, Meyer S, ten Broeke T, Leusen JH. Brandsma AM, et al. Immunol Rev. 2015 Nov;268(1):74-87. doi: 10.1111/imr.12332. Immunol Rev. 2015. PMID: 26497514 Review.

5

Clarifying the Confusion between Cytokine and Fc Receptor "Common Gamma Chain".

Brandsma AM, Hogarth PM, Nimmerjahn F, Leusen JH. Brandsma AM, et al. Immunity. 2016 Aug 16;45(2):225-6. doi: 10.1016/j.immuni.2016.07.006. Immunity. 2016. PMID: 27533005 Free article. No abstract available.

6

Single Nucleotide Polymorphisms of the High Affinity IgG Receptor FcγRI Reduce Immune Complex Binding and Downstream Effector Functions.

Brandsma AM, Ten Broeke T, van Dueren den Hollander E, Caniels TG, Kardol-Hoefnagel T, Kuball J, Leusen JHW. Brandsma AM, et al. J Immunol. 2017 Oct 1;199(7):2432-2439. doi: 10.4049/jimmunol.1601929. Epub 2017 Aug 16. J Immunol. 2017. PMID: 28814603

7

Mechanisms of inside-out signaling of the high-affinity IgG receptor FcγRI.

Brandsma AM, Schwartz SL, Wester MJ, Valley CC, Blezer GLA, Vidarsson G, Lidke KA, Ten Broeke T, Lidke DS, Leusen JHW. Brandsma AM, et al. Sci Signal. 2018 Jul 24;11(540):eaaq0891. doi: 10.1126/scisignal.aaq0891. Sci Signal. 2018. PMID: 30042128 Free PMC article.

8

FcαRI Dynamics Are Regulated by GSK-3 and PKCζ During Cytokine Mediated Inside-Out Signaling.

Ten Broeke T, Honing H, Brandsma AM, Jacobino S, Bakema JE, Kanters D, van der Linden JAM, Bracke M, Koenderman L, Leusen JHW. Ten Broeke T, et al. Among authors: brandsma am. Front Immunol. 2019 Jan 31;9:3191. doi: 10.3389/fimmu.2018.03191. eCollection 2018. Front Immunol. 2019. PMID: 30766540 Free PMC article.

9

Glutaminyl cyclase is an enzymatic modifier of the CD47- SIRPα axis and a target for cancer immunotherapy.

Logtenberg MEW, Jansen JHM, Raaben M, Toebes M, Franke K, Brandsma AM, Matlung HL, Fauster A, Gomez-Eerland R, Bakker NAM, van der Schot S, Marijt KA, Verdoes M, Haanen JBAG, van den Berg JH, Neefjes J, van den Berg TK, Brummelkamp TR, Leusen JHW, Scheeren FA, Schumacher TN. Logtenberg MEW, et al. Among authors: brandsma am. Nat Med. 2019 Apr;25(4):612-619. doi: 10.1038/s41591-019-0356-z. Epub 2019 Mar 4. Nat Med. 2019. PMID: 30833751 Free PMC article.

10

Potent Fc Receptor Signaling by IgA Leads to Superior Killing of Cancer Cells by Neutrophils Compared to IgG.

Brandsma AM, Bondza S, Evers M, Koutstaal R, Nederend M, Jansen JHM, Rösner T, Valerius T, Leusen JHW, Ten Broeke T. Brandsma AM, et al. Front Immunol. 2019 Apr 11;10:704. doi: 10.3389/fimmu.2019.00704. eCollection 2019. Front Immunol. 2019. PMID: 31031746 Free PMC article.

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