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A high-resolution 3D atlas of the spectrum of tuberculous and COVID-19 lung lesions.
Wells G, Glasgow JN, Nargan K, Lumamba K, Madansein R, Maharaj K, Perumal LY, Matthew M, Hunter RL, Pacl H, Peabody Lever JE, Stanford DD, Singh SP, Bajpai P, Manne U, Benson PV, Rowe SM, le Roux S, Sigal A, Tshibalanganda M, Wells C, du Plessis A, Msimang M, Naidoo T, Steyn AJC. Wells G, et al. Among authors: madansein r. EMBO Mol Med. 2022 Nov 8;14(11):e16283. doi: 10.15252/emmm.202216283. Epub 2022 Oct 26. EMBO Mol Med. 2022. PMID: 36285507 Free PMC article.
Ferritin H Deficiency in Myeloid Compartments Dysregulates Host Energy Metabolism and Increases Susceptibility to Mycobacterium tuberculosis Infection.
Reddy VP, Chinta KC, Saini V, Glasgow JN, Hull TD, Traylor A, Rey-Stolle F, Soares MP, Madansein R, Rahman MA, Barbas C, Nargan K, Naidoo T, Ramdial PK, George JF, Agarwal A, Steyn AJC. Reddy VP, et al. Among authors: madansein r. Front Immunol. 2018 May 3;9:860. doi: 10.3389/fimmu.2018.00860. eCollection 2018. Front Immunol. 2018. PMID: 29774023 Free PMC article.
Microanatomic Distribution of Myeloid Heme Oxygenase-1 Protects against Free Radical-Mediated Immunopathology in Human Tuberculosis.
Chinta KC, Rahman MA, Saini V, Glasgow JN, Reddy VP, Lever JM, Nhamoyebonde S, Leslie A, Wells RM, Traylor A, Madansein R, Siegal GP, Antony VB, Deshane J, Wells G, Nargan K, George JF, Ramdial PK, Agarwal A, Steyn AJC. Chinta KC, et al. Among authors: madansein r. Cell Rep. 2018 Nov 13;25(7):1938-1952.e5. doi: 10.1016/j.celrep.2018.10.073. Cell Rep. 2018. PMID: 30428359 Free PMC article.
Microanatomic Distribution of Myeloid Heme Oxygenase-1 Protects against Free Radical-Mediated Immunopathology in Human Tuberculosis.
Chinta KC, Rahman MA, Saini V, Glasgow JN, Reddy VP, Lever JM, Nhamoyebonde S, Leslie A, Wells RM, Traylor A, Madansein R, Siegal GP, Antony VB, Deshane J, Wells G, Nargan K, George JF, Ramdial PK, Agarwal A, Steyn AJC. Chinta KC, et al. Among authors: madansein r. Cell Rep. 2019 Sep 17;28(12):3286. doi: 10.1016/j.celrep.2019.08.081. Cell Rep. 2019. PMID: 31533049 Free PMC article. No abstract available.
Tissue-resident-like CD4+ T cells secreting IL-17 control Mycobacterium tuberculosis in the human lung.
Ogongo P, Tezera LB, Ardain A, Nhamoyebonde S, Ramsuran D, Singh A, Ng'oepe A, Karim F, Naidoo T, Khan K, Dullabh KJ, Fehlings M, Lee BH, Nardin A, Lindestam Arlehamn CS, Sette A, Behar SM, Steyn AJ, Madansein R, Kløverpris HN, Elkington PT, Leslie A. Ogongo P, et al. Among authors: madansein r. J Clin Invest. 2021 May 17;131(10):e142014. doi: 10.1172/JCI142014. J Clin Invest. 2021. PMID: 33848273 Free PMC article. Clinical Trial.
Micro-Computed Tomography Analysis of the Human Tuberculous Lung Reveals Remarkable Heterogeneity in Three-dimensional Granuloma Morphology.
Wells G, Glasgow JN, Nargan K, Lumamba K, Madansein R, Maharaj K, Hunter RL, Naidoo T, Coetzer L, le Roux S, du Plessis A, Steyn AJC. Wells G, et al. Among authors: madansein r. Am J Respir Crit Care Med. 2021 Sep 1;204(5):583-595. doi: 10.1164/rccm.202101-0032OC. Am J Respir Crit Care Med. 2021. PMID: 34015247 Free PMC article.
Similar Antibody Responses Against Severe Acute Respiratory Syndrome Coronavirus 2 in Individuals Living Without and With Human Immunodeficiency Virus on Antiretroviral Therapy During the First South African Infection Wave.
Snyman J, Hwa SH, Krause R, Muema D, Reddy T, Ganga Y, Karim F, Leslie A, Sigal A, Ndung'u T; COVID-19 Mechanisms and Multi-omics at the Intersection of TB and HIV in KwaZulu-Natal (COMMIT-KZN Team). Snyman J, et al. Clin Infect Dis. 2022 Aug 24;75(1):e249-e256. doi: 10.1093/cid/ciab758. Clin Infect Dis. 2022. PMID: 34472583 Free PMC article.
HIV status alters disease severity and immune cell responses in Beta variant SARS-CoV-2 infection wave.
Karim F, Gazy I, Cele S, Zungu Y, Krause R, Bernstein M, Khan K, Ganga Y, Rodel H, Mthabela N, Mazibuko M, Muema D, Ramjit D, Ndung'u T, Hanekom W, Gosnell B; COMMIT-KZN Team; Lessells RJ, Wong EB, de Oliveira T, Moosa MS, Lustig G, Leslie A, Kløverpris H, Sigal A. Karim F, et al. Elife. 2021 Oct 5;10:e67397. doi: 10.7554/eLife.67397. Elife. 2021. PMID: 34608862 Free PMC article.
Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control.
Gideon HP, Hughes TK, Tzouanas CN, Wadsworth MH 2nd, Tu AA, Gierahn TM, Peters JM, Hopkins FF, Wei JR, Kummerlowe C, Grant NL, Nargan K, Phuah JY, Borish HJ, Maiello P, White AG, Winchell CG, Nyquist SK, Ganchua SKC, Myers A, Patel KV, Ameel CL, Cochran CT, Ibrahim S, Tomko JA, Frye LJ, Rosenberg JM, Shih A, Chao M, Klein E, Scanga CA, Ordovas-Montanes J, Berger B, Mattila JT, Madansein R, Love JC, Lin PL, Leslie A, Behar SM, Bryson B, Flynn JL, Fortune SM, Shalek AK. Gideon HP, et al. Among authors: madansein r. Immunity. 2022 May 10;55(5):827-846.e10. doi: 10.1016/j.immuni.2022.04.004. Epub 2022 Apr 27. Immunity. 2022. PMID: 35483355 Free PMC article.
39 results