Broekaart DWM - Search Results

1

Altered Extracellular Matrix as an Alternative Risk Factor for Epileptogenicity in Brain Tumors.

de Jong JM, Broekaart DWM, Bongaarts A, Mühlebner A, Mills JD, van Vliet EA, Aronica E. de Jong JM, et al. Among authors: broekaart dwm. Biomedicines. 2022 Oct 3;10(10):2475. doi: 10.3390/biomedicines10102475. Biomedicines. 2022. PMID: 36289737 Free PMC article. Review.

2

The Gelatinase Inhibitor ACT-03 Reduces Gliosis in the Rapid Kindling Rat Model of Epilepsy, and Attenuates Inflammation and Loss of Barrier Integrity In Vitro.

Broekaart DWM, Zimmer TS, Cohen ST, Tessers R, Anink JJ, de Vries HE, Gorter JA, Prades R, Aronica E, van Vliet EA. Broekaart DWM, et al. Biomedicines. 2022 Aug 29;10(9):2117. doi: 10.3390/biomedicines10092117. Biomedicines. 2022. PMID: 36140216 Free PMC article.

3

Increased expression of (immuno)proteasome subunits during epileptogenesis is attenuated by inhibition of the mammalian target of rapamycin pathway.

Broekaart DWM, van Scheppingen J, Geijtenbeek KW, Zuidberg MRJ, Anink JJ, Baayen JC, Mühlebner A, Aronica E, Gorter JA, van Vliet EA. Broekaart DWM, et al. Epilepsia. 2017 Aug;58(8):1462-1472. doi: 10.1111/epi.13823. Epub 2017 Jun 23. Epilepsia. 2017. PMID: 28643873

4

miR147b: A novel key regulator of interleukin 1 beta-mediated inflammation in human astrocytes.

van Scheppingen J, Mills JD, Zimmer TS, Broekaart DWM, Iori V, Bongaarts A, Anink JJ, Iyer AM, Korotkov A, Jansen FE, van Hecke W, Spliet WG, van Rijen PC, Baayen JC, Vezzani A, van Vliet EA, Aronica E. van Scheppingen J, et al. Among authors: broekaart dwm. Glia. 2018 May;66(5):1082-1097. doi: 10.1002/glia.23302. Epub 2018 Jan 31. Glia. 2018. PMID: 29384235

5

Increased expression of matrix metalloproteinase 3 can be attenuated by inhibition of microRNA-155 in cultured human astrocytes.

Korotkov A, Broekaart DWM, van Scheppingen J, Anink JJ, Baayen JC, Idema S, Gorter JA, Aronica E, van Vliet EA. Korotkov A, et al. Among authors: broekaart dwm. J Neuroinflammation. 2018 Jul 21;15(1):211. doi: 10.1186/s12974-018-1245-y. J Neuroinflammation. 2018. PMID: 30031401 Free PMC article.

6

Activation of the innate immune system is evident throughout epileptogenesis and is associated with blood-brain barrier dysfunction and seizure progression.

Broekaart DWM, Anink JJ, Baayen JC, Idema S, de Vries HE, Aronica E, Gorter JA, van Vliet EA. Broekaart DWM, et al. Epilepsia. 2018 Oct;59(10):1931-1944. doi: 10.1111/epi.14550. Epub 2018 Sep 8. Epilepsia. 2018. PMID: 30194729

7

microRNA-132 is overexpressed in glia in temporal lobe epilepsy and reduces the expression of pro-epileptogenic factors in human cultured astrocytes.

Korotkov A, Broekaart DWM, Banchaewa L, Pustjens B, van Scheppingen J, Anink JJ, Baayen JC, Idema S, Gorter JA, van Vliet EA, Aronica E. Korotkov A, et al. Among authors: broekaart dwm. Glia. 2020 Jan;68(1):60-75. doi: 10.1002/glia.23700. Epub 2019 Aug 13. Glia. 2020. PMID: 31408236 Free PMC article.

8

Dysregulation of the MMP/TIMP Proteolytic System in Subependymal Giant Cell Astrocytomas in Patients With Tuberous Sclerosis Complex: Modulation of MMP by MicroRNA-320d In Vitro.

Bongaarts A, de Jong JM, Broekaart DWM, van Scheppingen J, Anink JJ, Mijnsbergen C, Jansen FE, Spliet WGM, den Dunnen WFA, Gruber VE, Scholl T, Hainfellner JA, Feucht M, Borkowska J, Kotulska K, Jozwiak S, Grajkowska W, Buccoliero AM, Caporalini C, Giordano F, Genitori L, Scicluna BP, Schouten-van Meeteren AYN, van Vliet EA, Mühlebner A, Mills JD, Aronica E. Bongaarts A, et al. Among authors: broekaart dwm. J Neuropathol Exp Neurol. 2020 Jul 1;79(7):777-790. doi: 10.1093/jnen/nlaa040. J Neuropathol Exp Neurol. 2020. PMID: 32472129 Free PMC article.

9

Tuberous Sclerosis Complex as Disease Model for Investigating mTOR-Related Gliopathy During Epileptogenesis.

Zimmer TS, Broekaart DWM, Gruber VE, van Vliet EA, Mühlebner A, Aronica E. Zimmer TS, et al. Among authors: broekaart dwm. Front Neurol. 2020 Sep 17;11:1028. doi: 10.3389/fneur.2020.01028. eCollection 2020. Front Neurol. 2020. PMID: 33041976 Free PMC article. Review.

10

The matrix metalloproteinase inhibitor IPR-179 has antiseizure and antiepileptogenic effects.

Broekaart DW, Bertran A, Jia S, Korotkov A, Senkov O, Bongaarts A, Mills JD, Anink JJ, Seco J, Baayen JC, Idema S, Chabrol E, Becker AJ, Wadman WJ, Tarragó T, Gorter JA, Aronica E, Prades R, Dityatev A, van Vliet EA. Broekaart DW, et al. J Clin Invest. 2021 Jan 4;131(1):e138332. doi: 10.1172/JCI138332. J Clin Invest. 2021. PMID: 33141761 Free PMC article.

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