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BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma.
Panditharatna E, Marques JG, Wang T, Trissal MC, Liu I, Jiang L, Beck A, Groves A, Dharia NV, Li D, Hoffman SE, Kugener G, Shaw ML, Mire HM, Hack OA, Dempster JM, Lareau C, Dai L, Sigua LH, Quezada MA, Stanton AJ, Wyatt M, Kalani Z, Goodale A, Vazquez F, Piccioni F, Doench JG, Root DE, Anastas JN, Jones KL, Conway AS, Stopka S, Regan MS, Liang Y, Seo HS, Song K, Bashyal P, Jerome WP, Mathewson ND, Dhe-Paganon S, Suvà ML, Carcaboso AM, Lavarino C, Mora J, Nguyen QD, Ligon KL, Shi Y, Agnihotri S, Agar NYR, Stegmaier K, Stiles CD, Monje M, Golub TR, Qi J, Filbin MG. Panditharatna E, et al. Among authors: seo hs. Cancer Discov. 2022 Dec 2;12(12):2880-2905. doi: 10.1158/2159-8290.CD-21-1491. Cancer Discov. 2022. PMID: 36305736 Free PMC article.
Design and characterization of bivalent BET inhibitors.
Tanaka M, Roberts JM, Seo HS, Souza A, Paulk J, Scott TG, DeAngelo SL, Dhe-Paganon S, Bradner JE. Tanaka M, et al. Among authors: seo hs. Nat Chem Biol. 2016 Dec;12(12):1089-1096. doi: 10.1038/nchembio.2209. Epub 2016 Oct 24. Nat Chem Biol. 2016. PMID: 27775715 Free PMC article.
Transcription control by the ENL YEATS domain in acute leukaemia.
Erb MA, Scott TG, Li BE, Xie H, Paulk J, Seo HS, Souza A, Roberts JM, Dastjerdi S, Buckley DL, Sanjana NE, Shalem O, Nabet B, Zeid R, Offei-Addo NK, Dhe-Paganon S, Zhang F, Orkin SH, Winter GE, Bradner JE. Erb MA, et al. Among authors: seo hs. Nature. 2017 Mar 9;543(7644):270-274. doi: 10.1038/nature21688. Epub 2017 Mar 1. Nature. 2017. PMID: 28241139 Free PMC article.
Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands.
Remillard D, Buckley DL, Paulk J, Brien GL, Sonnett M, Seo HS, Dastjerdi S, Wühr M, Dhe-Paganon S, Armstrong SA, Bradner JE. Remillard D, et al. Among authors: seo hs. Angew Chem Int Ed Engl. 2017 May 15;56(21):5738-5743. doi: 10.1002/anie.201611281. Epub 2017 Apr 18. Angew Chem Int Ed Engl. 2017. PMID: 28418626 Free PMC article.
Functional TRIM24 degrader via conjugation of ineffectual bromodomain and VHL ligands.
Gechijian LN, Buckley DL, Lawlor MA, Reyes JM, Paulk J, Ott CJ, Winter GE, Erb MA, Scott TG, Xu M, Seo HS, Dhe-Paganon S, Kwiatkowski NP, Perry JA, Qi J, Gray NS, Bradner JE. Gechijian LN, et al. Among authors: seo hs. Nat Chem Biol. 2018 Apr;14(4):405-412. doi: 10.1038/s41589-018-0010-y. Epub 2018 Mar 5. Nat Chem Biol. 2018. PMID: 29507391 Free PMC article.
Structural Implications of STAT3 and STAT5 SH2 Domain Mutations.
de Araujo ED, Orlova A, Neubauer HA, Bajusz D, Seo HS, Dhe-Paganon S, Keserű GM, Moriggl R, Gunning PT. de Araujo ED, et al. Among authors: seo hs. Cancers (Basel). 2019 Nov 8;11(11):1757. doi: 10.3390/cancers11111757. Cancers (Basel). 2019. PMID: 31717342 Free PMC article. Review.
Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling.
Valencia AM, Collings CK, Dao HT, St Pierre R, Cheng YC, Huang J, Sun ZY, Seo HS, Mashtalir N, Comstock DE, Bolonduro O, Vangos NE, Yeoh ZC, Dornon MK, Hermawan C, Barrett L, Dhe-Paganon S, Woolf CJ, Muir TW, Kadoch C. Valencia AM, et al. Among authors: seo hs. Cell. 2019 Nov 27;179(6):1342-1356.e23. doi: 10.1016/j.cell.2019.10.044. Epub 2019 Nov 20. Cell. 2019. PMID: 31759698 Free PMC article.
Identification of a Structural Determinant for Selective Targeting of HDMX.
Ben-Nun Y, Seo HS, Harvey EP, Hauseman ZJ, Wales TE, Newman CE, Cathcart AM, Engen JR, Dhe-Paganon S, Walensky LD. Ben-Nun Y, et al. Among authors: seo hs. Structure. 2020 Jul 7;28(7):847-857.e5. doi: 10.1016/j.str.2020.04.011. Epub 2020 Apr 30. Structure. 2020. PMID: 32359398 Free PMC article.
1,034 results