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In vivo biodistribution and pharmacokinetics of sotrovimab, a SARS-CoV-2 monoclonal antibody, in healthy cynomolgus monkeys.
Aweda TA, Cheng SH, Lenhard SC, Sepp A, Skedzielewski T, Hsu CY, Marshall S, Haag H, Kehler J, Jagdale P, Peter A, Schmid MA, Gehman A, Doan M, Mayer AP, Gorycki P, Fanget M, Colas C, Smith B, Maier CC, Alsaid H. Aweda TA, et al. Among authors: skedzielewski t. Eur J Nucl Med Mol Imaging. 2023 Feb;50(3):667-678. doi: 10.1007/s00259-022-06012-3. Epub 2022 Oct 28. Eur J Nucl Med Mol Imaging. 2023. PMID: 36305907 Free PMC article.
Immuno-PET Monitoring of CD8+ T Cell Infiltration Post ICOS Agonist Antibody Treatment Alone and in Combination with PD-1 Blocking Antibody Using a 89Zr Anti-CD8+ Mouse Minibody in EMT6 Syngeneic Tumor Mouse.
Alsaid H, Cheng SH, Bi M, Xie F, Rambo M, Skedzielewski T, Hoang B, Mohanan S, Comroe D, Gehman A, Hsu CY, Farhangi K, Tran H, Sherina V, Doan M, Groseclose MR, Hopson CB, Brett S, Wilson IA, Nicholls A, Ballas M, Waight JD, Jucker BM. Alsaid H, et al. Among authors: skedzielewski t. Mol Imaging Biol. 2023 Jun;25(3):528-540. doi: 10.1007/s11307-022-01781-7. Epub 2022 Oct 20. Mol Imaging Biol. 2023. PMID: 36266600 Free PMC article.
Multimodal imaging distribution assessment of a liposomal antibiotic in an infectious disease model.
Cheng SH, Groseclose MR, Mininger C, Bergstrom M, Zhang L, Lenhard SC, Skedzielewski T, Kelley ZD, Comroe D, Hong H, Cui H, Hoover JL, Rittenhouse S, Castellino S, Jucker BM, Alsaid H. Cheng SH, et al. Among authors: skedzielewski t. J Control Release. 2022 Dec;352:199-210. doi: 10.1016/j.jconrel.2022.08.061. Epub 2022 Oct 20. J Control Release. 2022. PMID: 36084816 Free article.
Non invasive imaging assessment of the biodistribution of GSK2849330, an ADCC and CDC optimized anti HER3 mAb, and its role in tumor macrophage recruitment in human tumor-bearing mice.
Alsaid H, Skedzielewski T, Rambo MV, Hunsinger K, Hoang B, Fieles W, Long ER, Tunstead J, Vugts DJ, Cleveland M, Clarke N, Matheny C, Jucker BM. Alsaid H, et al. Among authors: skedzielewski t. PLoS One. 2017 Apr 27;12(4):e0176075. doi: 10.1371/journal.pone.0176075. eCollection 2017. PLoS One. 2017. PMID: 28448604 Free PMC article.
The use of micro-CT imaging to examine and illustrate fetal skeletal abnormalities in Dutch Belted rabbits and to prove concordance with Alizarin Red stained skeletal examination.
Solomon HM, Murzyn S, Rendemonti J, Chapman S, Skedzielewski T, Jucker BM, Stanislaus D, Alsaid H. Solomon HM, et al. Among authors: skedzielewski t. Birth Defects Res. 2018 Feb 15;110(3):276-298. doi: 10.1002/bdr2.1168. Epub 2017 Nov 21. Birth Defects Res. 2018. PMID: 29159925
MRI/PET multimodal imaging of the innate immune response in skeletal muscle and draining lymph node post vaccination in rats.
Madi S, Xie F, Farhangi K, Hsu CY, Cheng SH, Aweda T, Radaram B, Slania S, Lambert T, Rambo M, Skedzielewski T, Cole A, Sherina V, McKearnan S, Tran H, Alsaid H, Doan M, Stokes AH, O'Hagan DT, Maruggi G, Bertholet S, Temmerman ST, Johnson R, Jucker BM. Madi S, et al. Among authors: skedzielewski t. Front Immunol. 2023 Jan 11;13:1081156. doi: 10.3389/fimmu.2022.1081156. eCollection 2022. Front Immunol. 2023. PMID: 36713458 Free PMC article.
In Vivo Imaging of Small Molecular Weight Peptides for Targeted Renal Drug Delivery: A Study in Normal and Polycystic Kidney Diseased Mice.
Lenhard SC, McAlexander A, Virtue A, Fieles W, Skedzielewski T, Rambo M, Trinh H, Cheng SH, Hong H, Isidro-Llobet A, Nadin A, Geske R, Klein JL, Lee D, Jucker BM, Hu E. Lenhard SC, et al. Among authors: skedzielewski t. J Pharmacol Exp Ther. 2019 Sep;370(3):786-795. doi: 10.1124/jpet.119.257022. Epub 2019 Apr 1. J Pharmacol Exp Ther. 2019. PMID: 30936291
11 results