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Severe COVID-19 is associated with fungal colonization of the nasopharynx and potent induction of IL-17 responses in the nasal epithelium.
Ziegler CGK, Owings AH, Miao VN, Navia AW, Tang Y, Bromley JD, Lotfy P, Sloan M, Laird H, Williams HB, George M, Drake RS, Pride Y, Abraham GE 3rd, Senitko M, Robinson TO, Lionakis MS, Shalek AK, Ordovas-Montanes J, Horwitz BH, Glover SC. Ziegler CGK, et al. Among authors: lionakis ms. medRxiv [Preprint]. 2022 Oct 26:2022.10.25.22281528. doi: 10.1101/2022.10.25.22281528. medRxiv. 2022. PMID: 36324802 Free PMC article. Preprint.
An enhanced IL17 and muted type I interferon nasal epithelial cell state characterizes severe COVID-19 with fungal coinfection.
Ziegler CGK, Owings AH, Galeas-Pena M, Kazer SW, Miao VN, Navia AW, Tang Y, Bromley JD, Lotfy P, Sloan M, Laird H, Williams HB, George M, Drake RS, Pride Y, Abraham GE 3rd, Senitko M, Robinson TO, Diamond G, Lionakis MS, Shalek AK, Ordovas-Montanes J, Horwitz BH, Glover SC. Ziegler CGK, et al. Among authors: lionakis ms. Microbiol Spectr. 2024 Jun 4;12(6):e0351623. doi: 10.1128/spectrum.03516-23. Epub 2024 Apr 30. Microbiol Spectr. 2024. PMID: 38687064 Free article.
Genetic susceptibility to fungal infection in children.
Ochoa S, Constantine GM, Lionakis MS. Ochoa S, et al. Among authors: lionakis ms. Curr Opin Pediatr. 2020 Dec;32(6):780-789. doi: 10.1097/MOP.0000000000000948. Curr Opin Pediatr. 2020. PMID: 33009121 Free PMC article. Review.
Host-virus chimeric events in SARS-CoV2 infected cells are infrequent and artifactual.
Yan B, Chakravorty S, Mirabelli C, Wang L, Trujillo-Ochoa JL, Chauss D, Kumar D, Lionakis MS, Olson MR, Wobus CE, Afzali B, Kazemian M. Yan B, et al. Among authors: lionakis ms. bioRxiv [Preprint]. 2021 Feb 17:2021.02.17.431704. doi: 10.1101/2021.02.17.431704. bioRxiv. 2021. PMID: 33619483 Free PMC article. Updated. Preprint.
Longitudinal single-cell epitope and RNA-sequencing reveals the immunological impact of type 1 interferon autoantibodies in critical COVID-19: Anti-IFN antibodies in critical COVID-19 correlate with poor ISG response and upregulation of LAIR1 surface protein in PBMCs.
van der Wijst MGP, Vazquez SE, Hartoularos GC, Bastard P, Grant T, Bueno R, Lee DS, Greenland JR, Sun Y, Perez R, Ogorodnikov A, Ward A, Mann SA, Lynch KL, Yun C, Havlir DV, Chamie G, Marquez C, Greenhouse B, Lionakis MS, Norris PJ, Dumont LJ, Kelly K, Zhang P, Zhang Q, Gervais A, Le Voyer T, Whatley A, Si Y, Byrne A, Combes AJ, Rao AA, Song YS; UCSF COMET consortium; Fragiadakis GK, Kangelaris K, Calfee CS, Erle DJ, Hendrickson C, Krummel MF, Woodruff PG, Langelier CR, Casanova JL, Derisi JL, Anderson MS, Ye CJ. van der Wijst MGP, et al. Among authors: lionakis ms. bioRxiv [Preprint]. 2021 Mar 10:2021.03.09.434529. doi: 10.1101/2021.03.09.434529. bioRxiv. 2021. PMID: 33758859 Free PMC article. Preprint.
Candida lipase packs a punch against IL-17.
Lubkin A, Lionakis MS. Lubkin A, et al. Among authors: lionakis ms. Cell Host Microbe. 2022 Nov 9;30(11):1503-1505. doi: 10.1016/j.chom.2022.10.006. Cell Host Microbe. 2022. PMID: 36356564 Free article.
Human CARD9: A Critical Molecule of Fungal Immune Surveillance.
Drummond RA, Franco LM, Lionakis MS. Drummond RA, et al. Among authors: lionakis ms. Front Immunol. 2018 Aug 6;9:1836. doi: 10.3389/fimmu.2018.01836. eCollection 2018. Front Immunol. 2018. PMID: 30127791 Free PMC article. Review.
249 results