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320 results

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Page 1
Helicobacter pylori eradication for primary prevention of peptic ulcer bleeding in older patients prescribed aspirin in primary care (HEAT): a randomised, double-blind, placebo-controlled trial.
Hawkey C, Avery A, Coupland CAC, Crooks C, Dumbleton J, Hobbs FDR, Kendrick D, Moore M, Morris C, Rubin G, Smith M, Stevenson D; HEAT Trialists. Hawkey C, et al. Among authors: hobbs fdr. Lancet. 2022 Nov 5;400(10363):1597-1606. doi: 10.1016/S0140-6736(22)01843-8. Lancet. 2022. PMID: 36335970 Free article. Clinical Trial.
Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial.
Butler CC, Hobbs FDR, Gbinigie OA, Rahman NM, Hayward G, Richards DB, Dorward J, Lowe DM, Standing JF, Breuer J, Khoo S, Petrou S, Hood K, Nguyen-Van-Tam JS, Patel MG, Saville BR, Marion J, Ogburn E, Allen J, Rutter H, Francis N, Thomas NPB, Evans P, Dobson M, Madden TA, Holmes J, Harris V, Png ME, Lown M, van Hecke O, Detry MA, Saunders CT, Fitzgerald M, Berry NS, Mwandigha L, Galal U, Mort S, Jani BD, Hart ND, Ahmed H, Butler D, McKenna M, Chalk J, Lavallee L, Hadley E, Cureton L, Benysek M, Andersson M, Coates M, Barrett S, Bateman C, Davies JC, Raymundo-Wood I, Ustianowski A, Carson-Stevens A, Yu LM, Little P; PANORAMIC Trial Collaborative Group. Butler CC, et al. Among authors: hobbs fdr. Lancet. 2023 Jan 28;401(10373):281-293. doi: 10.1016/S0140-6736(22)02597-1. Epub 2022 Dec 22. Lancet. 2023. PMID: 36566761 Free PMC article. Clinical Trial.
Gut microbiology of UK care home residents: a cross-sectional analysis from a randomised controlled trial.
Gillespie D, Wootton M, Ray R, Calder PC, Mandy Lau TM, Owen-Jones E, Lowe R, Davies L, Richards J, Hood K, Castro-Herrera V, Davies J, Francis NA, Hobbs FDR, Lown M, Moore M, Shepherd V, Butler CC. Gillespie D, et al. Among authors: hobbs fdr. Clin Microbiol Infect. 2023 Nov;29(11):1437-1442. doi: 10.1016/j.cmi.2023.08.001. Epub 2023 Aug 17. Clin Microbiol Infect. 2023. PMID: 37595801 Free article. Clinical Trial.
Development and external validation of a risk prediction model for falls in patients with an indication for antihypertensive treatment: retrospective cohort study.
Archer L, Koshiaris C, Lay-Flurrie S, Snell KIE, Riley RD, Stevens R, Banerjee A, Usher-Smith JA, Clegg A, Payne RA, Hobbs FDR, McManus RJ, Sheppard JP; STRAtifying Treatments In the multi-morbid Frail elderlY (STRATIFY) investigators. Archer L, et al. Among authors: hobbs fdr. BMJ. 2022 Nov 8;379:e070918. doi: 10.1136/bmj-2022-070918. BMJ. 2022. PMID: 36347531 Free PMC article.
Randomised controlled trial of population screening for atrial fibrillation in people aged 70 years and over to reduce stroke: protocol for the SAFER trial.
Mant J, Modi RN, Dymond A, Armstrong N, Burt J, Calvert P, Cowie M, Ding WY, Edwards D, Freedman B, Griffin SJ, Hoare S, Hobbs FDR, Johnson R, Kaptoge S, Lip GYH, Lobban T, Lown M, Lund J, McManus RJ, Mills MT, Morris S, Powell A, Proietti R, Sutton S, Sweeting M, Thom H, Williams K; SAFER author group. Mant J, et al. Among authors: hobbs fdr. BMJ Open. 2024 Apr 25;14(4):e082047. doi: 10.1136/bmjopen-2023-082047. BMJ Open. 2024. PMID: 38670614 Free PMC article. Clinical Trial.
Evaluation of the diagnostic accuracy of two point-of-care tests for COVID-19 when used in symptomatic patients in community settings in the UK primary care COVID diagnostic accuracy platform trial (RAPTOR-C19).
Nicholson BD, Turner PJ, Fanshawe TR, Williams AJ, Amirthalingam G, Tonner S, Zambon M, Body R, Davies K, Perera R, de Lusignan S, Hayward GN, Hobbs FDR; RAPTOR-C19 Study Group and the CONDOR Steering Committee. Nicholson BD, et al. Among authors: hobbs fdr. PLoS One. 2023 Jul 21;18(7):e0288612. doi: 10.1371/journal.pone.0288612. eCollection 2023. PLoS One. 2023. PMID: 37478103 Free PMC article. Clinical Trial.
Risk of severe COVID-19 outcomes after autumn 2022 COVID-19 booster vaccinations: a pooled analysis of national prospective cohort studies involving 7.4 million adults in England, Northern Ireland, Scotland and Wales.
Bedston S, Almaghrabi F, Patterson L, Agrawal U, Woolford L, Anand SN, Joy M, Crawford A, Goudie R, Byford R, Abbasizanjani H, Smith D, Laidlaw L, Akbari A, Sullivan C, Bradley DT, Lyons RA, de Lusignan S, Hobbs FDR, Robertson C, Sheikh SA, Shi T. Bedston S, et al. Among authors: hobbs fdr. Lancet Reg Health Eur. 2023 Dec 12;37:100816. doi: 10.1016/j.lanepe.2023.100816. eCollection 2024 Feb. Lancet Reg Health Eur. 2023. PMID: 38162515 Free PMC article.
Thrombocytopenic, thromboembolic and haemorrhagic events following second dose with BNT162b2 and ChAdOx1: self-controlled case series analysis of the English national sentinel cohort.
Joy M, Agrawal U, Fan X, Robertson C, Anand SN, Ordonez-Mena J, Byford R, Goudie R, Jamie G, Kar D, Williams J, Marsden GL, Tzortziou-Brown V, Sheikh SA, Hobbs FDR, de Lusignan S. Joy M, et al. Among authors: hobbs fdr. Lancet Reg Health Eur. 2023 Jul 18;32:100681. doi: 10.1016/j.lanepe.2023.100681. eCollection 2023 Sep. Lancet Reg Health Eur. 2023. PMID: 37671127 Free PMC article.
Correction: Benefits of Aldosterone Receptor Antagonism in Chronic Kidney Disease (BARACK D) trial-a multi-centre, prospective, randomised, open, blinded end-point, 36-month study of 2,616 patients within primary care with stage 3b chronic kidney disease to compare the efficacy of spironolactone 25 mg once daily in addition to routine care on mortality and cardiovascular outcomes versus routine care alone: study protocol for a randomized controlled trial.
Hill NR, Lasserson D, Thompson B, Perera-Salazar R, Wolstenholme J, Bower P, Blakeman T, Fitzmaurice D, Little P, Feder G, Qureshi N, Taal M, Townend J, Ferro C, McManus R, Hobbs FDR. Hill NR, et al. Among authors: hobbs fdr. Trials. 2022 Dec 12;23(1):999. doi: 10.1186/s13063-022-06972-9. Trials. 2022. PMID: 36510220 Free PMC article. No abstract available.
BLOod Test Trend for cancEr Detection (BLOTTED): protocol for an observational and prediction model development study using English primary care electronic health record data.
Virdee PS, Bankhead C, Koshiaris C, Drakesmith CW, Oke J, Withrow D, Swain S, Collins K, Chammas L, Tamm A, Zhu T, Morris E, Holt T, Birks J, Perera R, Hobbs FDR, Nicholson BD. Virdee PS, et al. Among authors: hobbs fdr. Diagn Progn Res. 2023 Jan 10;7(1):1. doi: 10.1186/s41512-022-00138-6. Diagn Progn Res. 2023. PMID: 36624489 Free PMC article.
320 results