Tian S - Search Results

1

A novel RIPK1 inhibitor reduces GVHD in mice via a nonimmunosuppressive mechanism that restores intestinal homeostasis.

Yu X, Ma H, Li B, Ji Y, Du Y, Liu S, Li Z, Hao Y, Tian S, Zhao C, Du Q, Jin Z, Zhu X, Tian Y, Chen X, Sun X, Yang C, Zhu F, Ju J, Zheng Y, Zhang W, Wang J, Yang T, Wang X, Li J, Xu X, Du S, Lu H, Ma F, Zhang H, Zhang Y, Zhang X, Hu S, He S. Yu X, et al. Among authors: tian s, tian y. Blood. 2023 Mar 2;141(9):1070-1086. doi: 10.1182/blood.2022017262. Blood. 2023. PMID: 36356302 Free PMC article.

2

Discovery of a 6-(pyridin-3-yl)benzo[d]thiazole template for optimization of hedgehog and PI3K/AKT/mTOR dual inhibitors.

Yang Z, Ma H, Sun Z, Luo L, Tian S, Zheng J, Zhang X. Yang Z, et al. Among authors: tian s. Bioorg Med Chem Lett. 2015 Sep 1;25(17):3665-70. doi: 10.1016/j.bmcl.2015.06.049. Epub 2015 Jun 18. Bioorg Med Chem Lett. 2015. PMID: 26119500

3

Identification of a New Series of Potent Adenosine A_2A Receptor Antagonists Based on 4-Amino-5-carbonitrile Pyrimidine Template for the Treatment of Parkinson's Disease.

Yang Z, Li L, Zheng J, Ma H, Tian S, Li J, Zhang H, Zhen X, Zhang X. Yang Z, et al. Among authors: tian s. ACS Chem Neurosci. 2016 Nov 16;7(11):1575-1584. doi: 10.1021/acschemneuro.6b00218. Epub 2016 Sep 9. ACS Chem Neurosci. 2016. PMID: 27569066

4

Design, Synthesis, and Structure-Activity Relationship of Tetrahydropyrido[4,3-d]pyrimidine Derivatives as Potent Smoothened Antagonists with in Vivo Activity.

Lu W, Liu Y, Ma H, Zheng J, Tian S, Sun Z, Luo L, Li J, Zhang H, Yang ZJ, Zhang X. Lu W, et al. Among authors: tian s. ACS Chem Neurosci. 2017 Sep 20;8(9):1980-1994. doi: 10.1021/acschemneuro.7b00153. Epub 2017 Jun 30. ACS Chem Neurosci. 2017. PMID: 28618224

5

Discovery of potent and novel smoothened antagonists via structure-based virtual screening and biological assays.

Lu W, Zhang D, Ma H, Tian S, Zheng J, Wang Q, Luo L, Zhang X. Lu W, et al. Among authors: tian s. Eur J Med Chem. 2018 Jul 15;155:34-48. doi: 10.1016/j.ejmech.2018.05.035. Epub 2018 May 23. Eur J Med Chem. 2018. PMID: 29857275

6

Structural optimization on a virtual screening hit of smoothened receptor.

Song S, Jiang J, Zhao L, Wang Q, Lu W, Zheng C, Zhang J, Ma H, Tian S, Zheng J, Luo L, Li Y, Yang ZJ, Zhang X. Song S, et al. Among authors: tian s. Eur J Med Chem. 2019 Jun 15;172:1-15. doi: 10.1016/j.ejmech.2019.03.057. Epub 2019 Mar 26. Eur J Med Chem. 2019. PMID: 30939349

7

Structural optimization of aminopyrimidine-based CXCR4 antagonists.

Zhu F, Wang Y, Du Q, Ge W, Li Z, Wang X, Fu C, Luo L, Tian S, Ma H, Zheng J, Zhang Y, Sun X, He S, Zhang X. Zhu F, et al. Among authors: tian s. Eur J Med Chem. 2020 Feb 1;187:111914. doi: 10.1016/j.ejmech.2019.111914. Epub 2019 Nov 26. Eur J Med Chem. 2020. PMID: 31806538

8

Design, Synthesis, and Characterization of Novel CXCR4 Antagonists Featuring Cyclic Amines.

Lin Y, Li Z, Ma H, Wang Y, Wang X, Song S, Zhao L, Wu S, Tian S, Fu C, Luo L, Zhu F, He S, Zheng J, Zhang X. Lin Y, et al. Among authors: tian s. ChemMedChem. 2020 Jul 3;15(13):1150-1162. doi: 10.1002/cmdc.202000268. Epub 2020 May 29. ChemMedChem. 2020. PMID: 32391652

9

Ring closure strategy leads to potent RIPK3 inhibitors.

Wu S, Xu C, Xia K, Lin Y, Tian S, Ma H, Ji Y, Zhu F, He S, Zhang X. Wu S, et al. Among authors: tian s. Eur J Med Chem. 2021 May 5;217:113327. doi: 10.1016/j.ejmech.2021.113327. Epub 2021 Mar 9. Eur J Med Chem. 2021. PMID: 33730678

10

Design, synthesis, and evaluation of potent RIPK1 inhibitors with in vivo anti-inflammatory activity.

Li Z, Hao Y, Yang C, Yang Q, Wu S, Ma H, Tian S, Lu H, Wang J, Yang T, He S, Zhang X. Li Z, et al. Among authors: tian s. Eur J Med Chem. 2022 Jan 15;228:114036. doi: 10.1016/j.ejmech.2021.114036. Epub 2021 Dec 8. Eur J Med Chem. 2022. PMID: 34906762

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

5,113 results

Search Page