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BI 456906: Discovery and preclinical pharmacology of a novel GCGR/GLP-1R dual agonist with robust anti-obesity efficacy.
Zimmermann T, Thomas L, Baader-Pagler T, Haebel P, Simon E, Reindl W, Bajrami B, Rist W, Uphues I, Drucker DJ, Klein H, Santhanam R, Hamprecht D, Neubauer H, Augustin R. Zimmermann T, et al. Among authors: klein h. Mol Metab. 2022 Dec;66:101633. doi: 10.1016/j.molmet.2022.101633. Epub 2022 Nov 7. Mol Metab. 2022. PMID: 36356832 Free PMC article.
FAM3D: A gut secreted protein and its potential in the regulation of glucose metabolism.
Moser C, Gosselé KA, Balaz M, Balazova L, Horvath C, Künzle P, Okreglicka KM, Li F, Blüher M, Stierstorfer B, Hess E, Lamla T, Hamilton B, Klein H, Neubauer H, Wolfrum C, Wolfrum S. Moser C, et al. Among authors: klein h. Peptides. 2023 Sep;167:171047. doi: 10.1016/j.peptides.2023.171047. Epub 2023 Jun 14. Peptides. 2023. PMID: 37328068 Free article.
Riboswitch-controlled IL-12 gene therapy reduces hepatocellular cancer in mice.
Düchs MJ, Kratzer RF, Vieyra-Garcia P, Strobel B, Schönberger T, Groß P, Aljayyoussi G, Gupta A, Lang I, Klein H, Morilla SM, Hopf S, Park J, Kreuz S, Klugmann M, Igney FH. Düchs MJ, et al. Among authors: klein h. Front Immunol. 2024 Mar 15;15:1360063. doi: 10.3389/fimmu.2024.1360063. eCollection 2024. Front Immunol. 2024. PMID: 38558809 Free PMC article.
Risks of Restrictive Versus Liberal Red Blood Cell Transfusion Strategies in Patients with Cardiovascular Disease: An Updated Meta-Analysis.
Applefeld WN, Ford V, Cortes-Puch I, Wang J, Sun J, Shields TC, Danner RL, Eichacker PQ, Solomon MA, Klein HG, Natanson C. Applefeld WN, et al. Among authors: klein hg. Circ Cardiovasc Qual Outcomes. 2024 May 15. doi: 10.1161/CIRCOUTCOMES.124.010957. Online ahead of print. Circ Cardiovasc Qual Outcomes. 2024. PMID: 38747144 Free article. No abstract available.
Therapy of Type 2 Diabetes.
Landgraf R, Aberle J, Birkenfeld AL, Gallwitz B, Kellerer M, Klein HH, Müller-Wieland D, Nauck MA, Wiesner T, Siegel E. Landgraf R, et al. Among authors: klein hh. Exp Clin Endocrinol Diabetes. 2024 Apr 10. doi: 10.1055/a-2166-6755. Online ahead of print. Exp Clin Endocrinol Diabetes. 2024. PMID: 38599610 Free article. No abstract available.
Cell subtype-specific effects of genetic variation in the Alzheimer's disease brain.
Fujita M, Gao Z, Zeng L, McCabe C, White CC, Ng B, Green GS, Rozenblatt-Rosen O, Phillips D, Amir-Zilberstein L, Lee H, Pearse RV 2nd, Khan A, Vardarajan BN, Kiryluk K, Ye CJ, Klein HU, Wang G, Regev A, Habib N, Schneider JA, Wang Y, Young-Pearse T, Mostafavi S, Bennett DA, Menon V, De Jager PL. Fujita M, et al. Among authors: klein hu. Nat Genet. 2024 Apr;56(4):605-614. doi: 10.1038/s41588-024-01685-y. Epub 2024 Mar 21. Nat Genet. 2024. PMID: 38514782
2,612 results