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TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4.
Gratuze M, Schlachetzki JCM, D'Oliveira Albanus R, Jain N, Novotny B, Brase L, Rodriguez L, Mansel C, Kipnis M, O'Brien S, Pasillas MP, Lee C, Manis M, Colonna M, Harari O, Glass CK, Ulrich JD, Holtzman DM. Gratuze M, et al. Among authors: holtzman dm. Neuron. 2023 Jan 18;111(2):202-219.e7. doi: 10.1016/j.neuron.2022.10.022. Epub 2022 Nov 10. Neuron. 2023. PMID: 36368315 Free PMC article.
The bad seed in Alzheimer's disease.
Fryer JD, Holtzman DM. Fryer JD, et al. Among authors: holtzman dm. Neuron. 2005 Jul 21;47(2):167-8. doi: 10.1016/j.neuron.2005.07.002. Neuron. 2005. PMID: 16039556 Free article.
ApoE promotes the proteolytic degradation of Abeta.
Jiang Q, Lee CY, Mandrekar S, Wilkinson B, Cramer P, Zelcer N, Mann K, Lamb B, Willson TM, Collins JL, Richardson JC, Smith JD, Comery TA, Riddell D, Holtzman DM, Tontonoz P, Landreth GE. Jiang Q, et al. Among authors: holtzman dm. Neuron. 2008 Jun 12;58(5):681-93. doi: 10.1016/j.neuron.2008.04.010. Neuron. 2008. PMID: 18549781 Free PMC article.
The role of apolipoprotein E in Alzheimer's disease.
Kim J, Basak JM, Holtzman DM. Kim J, et al. Among authors: holtzman dm. Neuron. 2009 Aug 13;63(3):287-303. doi: 10.1016/j.neuron.2009.06.026. Neuron. 2009. PMID: 19679070 Free PMC article. Review.
GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease.
Cruchaga C, Kauwe JS, Harari O, Jin SC, Cai Y, Karch CM, Benitez BA, Jeng AT, Skorupa T, Carrell D, Bertelsen S, Bailey M, McKean D, Shulman JM, De Jager PL, Chibnik L, Bennett DA, Arnold SE, Harold D, Sims R, Gerrish A, Williams J, Van Deerlin VM, Lee VM, Shaw LM, Trojanowski JQ, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD, Peskind ER, Galasko D, Fagan AM, Holtzman DM, Morris JC; GERAD Consortium; Alzheimer’s Disease Neuroimaging Initiative (ADNI); Alzheimer Disease Genetic Consortium (ADGC); Goate AM. Cruchaga C, et al. Among authors: holtzman dm. Neuron. 2013 Apr 24;78(2):256-68. doi: 10.1016/j.neuron.2013.02.026. Epub 2013 Apr 4. Neuron. 2013. PMID: 23562540 Free PMC article.
Biomarker modeling of Alzheimer's disease.
Jack CR Jr, Holtzman DM. Jack CR Jr, et al. Among authors: holtzman dm. Neuron. 2013 Dec 18;80(6):1347-58. doi: 10.1016/j.neuron.2013.12.003. Neuron. 2013. PMID: 24360540 Free PMC article. Review.
610 results