Gnanapragasam PNP - Search Results

1

Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes.

Fan C, Cohen AA, Park M, Hung AF, Keeffe JR, Gnanapragasam PNP, Lee YE, Gao H, Kakutani LM, Wu Z, Kleanthous H, Malecek KE, Williams JC, Bjorkman PJ. Fan C, et al. Among authors: gnanapragasam pnp. Immunity. 2022 Dec 13;55(12):2419-2435.e10. doi: 10.1016/j.immuni.2022.10.019. Epub 2022 Oct 27. Immunity. 2022. PMID: 36370711 Free PMC article.

2

Design and expression of a dimeric form of human immunodeficiency virus type 1 antibody 2G12 with increased neutralization potency.

West AP Jr, Galimidi RP, Foglesong CP, Gnanapragasam PN, Huey-Tubman KE, Klein JS, Suzuki MD, Tiangco NE, Vielmetter J, Bjorkman PJ. West AP Jr, et al. J Virol. 2009 Jan;83(1):98-104. doi: 10.1128/JVI.01564-08. Epub 2008 Oct 22. J Virol. 2009. PMID: 18945777 Free PMC article.

3

Examination of the contributions of size and avidity to the neutralization mechanisms of the anti-HIV antibodies b12 and 4E10.

Klein JS, Gnanapragasam PN, Galimidi RP, Foglesong CP, West AP Jr, Bjorkman PJ. Klein JS, et al. Proc Natl Acad Sci U S A. 2009 May 5;106(18):7385-90. doi: 10.1073/pnas.0811427106. Epub 2009 Apr 16. Proc Natl Acad Sci U S A. 2009. PMID: 19372381 Free PMC article.

4

Evaluation of CD4-CD4i antibody architectures yields potent, broadly cross-reactive anti-human immunodeficiency virus reagents.

West AP Jr, Galimidi RP, Foglesong CP, Gnanapragasam PN, Klein JS, Bjorkman PJ. West AP Jr, et al. J Virol. 2010 Jan;84(1):261-9. doi: 10.1128/JVI.01528-09. J Virol. 2010. PMID: 19864392 Free PMC article.

5

A dimeric form of the HIV-1 antibody 2G12 elicits potent antibody-dependent cellular cytotoxicity.

Klein JS, Webster A, Gnanapragasam PN, Galimidi RP, Bjorkman PJ. Klein JS, et al. AIDS. 2010 Jul 17;24(11):1633-40. doi: 10.1097/qad.0b013e32833ad8c8. AIDS. 2010. PMID: 20597163 Free PMC article.

6

Designed oligomers of cyanovirin-N show enhanced HIV neutralization.

Keeffe JR, Gnanapragasam PN, Gillespie SK, Yong J, Bjorkman PJ, Mayo SL. Keeffe JR, et al. Proc Natl Acad Sci U S A. 2011 Aug 23;108(34):14079-84. doi: 10.1073/pnas.1108777108. Epub 2011 Jul 28. Proc Natl Acad Sci U S A. 2011. PMID: 21799112 Free PMC article.

7

Single-chain Fv-based anti-HIV proteins: potential and limitations.

West AP Jr, Galimidi RP, Gnanapragasam PN, Bjorkman PJ. West AP Jr, et al. J Virol. 2012 Jan;86(1):195-202. doi: 10.1128/JVI.05848-11. Epub 2011 Oct 19. J Virol. 2012. PMID: 22013046 Free PMC article.

8

Increasing the potency and breadth of an HIV antibody by using structure-based rational design.

Diskin R, Scheid JF, Marcovecchio PM, West AP Jr, Klein F, Gao H, Gnanapragasam PN, Abadir A, Seaman MS, Nussenzweig MC, Bjorkman PJ. Diskin R, et al. Science. 2011 Dec 2;334(6060):1289-93. doi: 10.1126/science.1213782. Epub 2011 Oct 27. Science. 2011. PMID: 22033520 Free PMC article.

9

Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies.

Mouquet H, Scharf L, Euler Z, Liu Y, Eden C, Scheid JF, Halper-Stromberg A, Gnanapragasam PN, Spencer DI, Seaman MS, Schuitemaker H, Feizi T, Nussenzweig MC, Bjorkman PJ. Mouquet H, et al. Proc Natl Acad Sci U S A. 2012 Nov 20;109(47):E3268-77. doi: 10.1073/pnas.1217207109. Epub 2012 Oct 30. Proc Natl Acad Sci U S A. 2012. PMID: 23115339 Free PMC article.

10

Antibody 8ANC195 reveals a site of broad vulnerability on the HIV-1 envelope spike.

Scharf L, Scheid JF, Lee JH, West AP Jr, Chen C, Gao H, Gnanapragasam PN, Mares R, Seaman MS, Ward AB, Nussenzweig MC, Bjorkman PJ. Scharf L, et al. Cell Rep. 2014 May 8;7(3):785-95. doi: 10.1016/j.celrep.2014.04.001. Epub 2014 Apr 24. Cell Rep. 2014. PMID: 24767986 Free PMC article.

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