Lander GC - Search Results

1

Molecular glue CELMoD compounds are regulators of cereblon conformation.

Watson ER, Novick S, Matyskiela ME, Chamberlain PP, H de la Peña A, Zhu J, Tran E, Griffin PR, Wertz IE, Lander GC. Watson ER, et al. Among authors: lander gc. Science. 2022 Nov 4;378(6619):549-553. doi: 10.1126/science.add7574. Epub 2022 Nov 3. Science. 2022. PMID: 36378961 Free PMC article.

2

The structure of an infectious P22 virion shows the signal for headful DNA packaging.

Lander GC, Tang L, Casjens SR, Gilcrease EB, Prevelige P, Poliakov A, Potter CS, Carragher B, Johnson JE. Lander GC, et al. Science. 2006 Jun 23;312(5781):1791-5. doi: 10.1126/science.1127981. Epub 2006 May 18. Science. 2006. PMID: 16709746

3

Complete subunit architecture of the proteasome regulatory particle.

Lander GC, Estrin E, Matyskiela ME, Bashore C, Nogales E, Martin A. Lander GC, et al. Nature. 2012 Jan 11;482(7384):186-91. doi: 10.1038/nature10774. Nature. 2012. PMID: 22237024 Free PMC article.

4

Conformational switching of the 26S proteasome enables substrate degradation.

Matyskiela ME, Lander GC, Martin A. Matyskiela ME, et al. Among authors: lander gc. Nat Struct Mol Biol. 2013 Jul;20(7):781-8. doi: 10.1038/nsmb.2616. Epub 2013 Jun 16. Nat Struct Mol Biol. 2013. PMID: 23770819 Free PMC article.

5

Ubp6 deubiquitinase controls conformational dynamics and substrate degradation of the 26S proteasome.

Bashore C, Dambacher CM, Goodall EA, Matyskiela ME, Lander GC, Martin A. Bashore C, et al. Among authors: lander gc. Nat Struct Mol Biol. 2015 Sep;22(9):712-9. doi: 10.1038/nsmb.3075. Epub 2015 Aug 24. Nat Struct Mol Biol. 2015. PMID: 26301997 Free PMC article.

6

A novel cereblon modulator recruits GSPT1 to the CRL4(CRBN) ubiquitin ligase.

Matyskiela ME, Lu G, Ito T, Pagarigan B, Lu CC, Miller K, Fang W, Wang NY, Nguyen D, Houston J, Carmel G, Tran T, Riley M, Nosaka L, Lander GC, Gaidarova S, Xu S, Ruchelman AL, Handa H, Carmichael J, Daniel TO, Cathers BE, Lopez-Girona A, Chamberlain PP. Matyskiela ME, et al. Among authors: lander gc. Nature. 2016 Jul 14;535(7611):252-7. doi: 10.1038/nature18611. Epub 2016 Jun 22. Nature. 2016. PMID: 27338790

7

Structure of the mitochondrial inner membrane AAA+ protease YME1 gives insight into substrate processing.

Puchades C, Rampello AJ, Shin M, Giuliano CJ, Wiseman RL, Glynn SE, Lander GC. Puchades C, et al. Among authors: lander gc. Science. 2017 Nov 3;358(6363):eaao0464. doi: 10.1126/science.aao0464. Science. 2017. PMID: 29097521 Free PMC article.

8

Structure of the cold- and menthol-sensing ion channel TRPM8.

Yin Y, Wu M, Zubcevic L, Borschel WF, Lander GC, Lee SY. Yin Y, et al. Among authors: lander gc. Science. 2018 Jan 12;359(6372):237-241. doi: 10.1126/science.aan4325. Epub 2017 Dec 7. Science. 2018. PMID: 29217583 Free PMC article.

9

Cryo-EM structure of a mitochondrial calcium uniporter.

Yoo J, Wu M, Yin Y, Herzik MA Jr, Lander GC, Lee SY. Yoo J, et al. Among authors: lander gc. Science. 2018 Aug 3;361(6401):506-511. doi: 10.1126/science.aar4056. Epub 2018 Jun 28. Science. 2018. PMID: 29954988 Free PMC article.

10

Substrate-engaged 26S proteasome structures reveal mechanisms for ATP-hydrolysis-driven translocation.

de la Peña AH, Goodall EA, Gates SN, Lander GC, Martin A. de la Peña AH, et al. Among authors: lander gc. Science. 2018 Nov 30;362(6418):eaav0725. doi: 10.1126/science.aav0725. Epub 2018 Oct 11. Science. 2018. PMID: 30309908 Free PMC article.

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