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Molecular glue CELMoD compounds are regulators of cereblon conformation.
Watson ER, Novick S, Matyskiela ME, Chamberlain PP, H de la Peña A, Zhu J, Tran E, Griffin PR, Wertz IE, Lander GC. Watson ER, et al. Science. 2022 Nov 4;378(6619):549-553. doi: 10.1126/science.add7574. Epub 2022 Nov 3. Science. 2022. PMID: 36378961 Free PMC article.
Allosteric differences dictate GroEL complementation of E. coli.
Sivinski J, Ngo D, Zerio CJ, Ambrose AJ, Watson ER, Kaneko LK, Kostelic MM, Stevens M, Ray AM, Park Y, Wu C, Marty MT, Hoang QQ, Zhang DD, Lander GC, Johnson SM, Chapman E. Sivinski J, et al. Among authors: watson er. FASEB J. 2022 Mar;36(3):e22198. doi: 10.1096/fj.202101708RR. FASEB J. 2022. PMID: 35199390 Free PMC article.
Deconstructing heterogeneity of replicative senescence in human mesenchymal stem cells at single cell resolution.
Taherian Fard A, Leeson HC, Aguado J, Pietrogrande G, Power D, Gómez-Inclán C, Zheng H, Nelson CB, Soheilmoghaddam F, Glass N, Dharmaratne M, Watson ER, Lu J, Martin S, Pickett HA, Cooper-White J, Wolvetang EJ, Mar JC. Taherian Fard A, et al. Among authors: watson er. Geroscience. 2024 Feb;46(1):999-1015. doi: 10.1007/s11357-023-00829-y. Epub 2023 Jun 14. Geroscience. 2024. PMID: 37314668 Free PMC article.
APC7 mediates ubiquitin signaling in constitutive heterochromatin in the developing mammalian brain.
Ferguson CJ, Urso O, Bodrug T, Gassaway BM, Watson ER, Prabu JR, Lara-Gonzalez P, Martinez-Chacin RC, Wu DY, Brigatti KW, Puffenberger EG, Taylor CM, Haas-Givler B, Jinks RN, Strauss KA, Desai A, Gabel HW, Gygi SP, Schulman BA, Brown NG, Bonni A. Ferguson CJ, et al. Among authors: watson er. Mol Cell. 2022 Jan 6;82(1):90-105.e13. doi: 10.1016/j.molcel.2021.11.031. Epub 2021 Dec 22. Mol Cell. 2022. PMID: 34942119 Free PMC article.
Gene expression and cell identity controlled by anaphase-promoting complex.
Oh E, Mark KG, Mocciaro A, Watson ER, Prabu JR, Cha DD, Kampmann M, Gamarra N, Zhou CY, Rape M. Oh E, et al. Among authors: watson er. Nature. 2020 Mar;579(7797):136-140. doi: 10.1038/s41586-020-2034-1. Epub 2020 Feb 19. Nature. 2020. PMID: 32076268 Free PMC article.
Protein engineering of a ubiquitin-variant inhibitor of APC/C identifies a cryptic K48 ubiquitin chain binding site.
Watson ER, Grace CRR, Zhang W, Miller DJ, Davidson IF, Prabu JR, Yu S, Bolhuis DL, Kulko ET, Vollrath R, Haselbach D, Stark H, Peters JM, Brown NG, Sidhu SS, Schulman BA. Watson ER, et al. Proc Natl Acad Sci U S A. 2019 Aug 27;116(35):17280-17289. doi: 10.1073/pnas.1902889116. Epub 2019 Jul 26. Proc Natl Acad Sci U S A. 2019. PMID: 31350353 Free PMC article.
47 results