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SARS-CoV-2 variant Alpha has a spike-dependent replication advantage over the ancestral B.1 strain in human cells with low ACE2 expression.
Niemeyer D, Stenzel S, Veith T, Schroeder S, Friedmann K, Weege F, Trimpert J, Heinze J, Richter A, Jansen J, Emanuel J, Kazmierski J, Pott F, Jeworowski LM, Olmer R, Jaboreck MC, Tenner B, Papies J, Walper F, Schmidt ML, Heinemann N, Möncke-Buchner E, Baumgardt M, Hoffmann K, Widera M, Thao TTN, Balázs A, Schulze J, Mache C, Jones TC, Morkel M, Ciesek S, Hanitsch LG, Mall MA, Hocke AC, Thiel V, Osterrieder K, Wolff T, Martin U, Corman VM, Müller MA, Goffinet C, Drosten C. Niemeyer D, et al. Among authors: thiel v. PLoS Biol. 2022 Nov 16;20(11):e3001871. doi: 10.1371/journal.pbio.3001871. eCollection 2022 Nov. PLoS Biol. 2022. PMID: 36383605 Free PMC article.
Targeting membrane-bound viral RNA synthesis reveals potent inhibition of diverse coronaviruses including the middle East respiratory syndrome virus.
Lundin A, Dijkman R, Bergström T, Kann N, Adamiak B, Hannoun C, Kindler E, Jónsdóttir HR, Muth D, Kint J, Forlenza M, Müller MA, Drosten C, Thiel V, Trybala E. Lundin A, et al. Among authors: thiel v. PLoS Pathog. 2014 May 29;10(5):e1004166. doi: 10.1371/journal.ppat.1004166. eCollection 2014 May. PLoS Pathog. 2014. PMID: 24874215 Free PMC article.
Evidence for an Ancestral Association of Human Coronavirus 229E with Bats.
Corman VM, Baldwin HJ, Tateno AF, Zerbinati RM, Annan A, Owusu M, Nkrumah EE, Maganga GD, Oppong S, Adu-Sarkodie Y, Vallo P, da Silva Filho LV, Leroy EM, Thiel V, van der Hoek L, Poon LL, Tschapka M, Drosten C, Drexler JF. Corman VM, et al. Among authors: thiel v. J Virol. 2015 Dec;89(23):11858-70. doi: 10.1128/JVI.01755-15. Epub 2015 Sep 16. J Virol. 2015. PMID: 26378164 Free PMC article.
Link of a ubiquitous human coronavirus to dromedary camels.
Corman VM, Eckerle I, Memish ZA, Liljander AM, Dijkman R, Jonsdottir H, Juma Ngeiywa KJ, Kamau E, Younan M, Al Masri M, Assiri A, Gluecks I, Musa BE, Meyer B, Müller MA, Hilali M, Bornstein S, Wernery U, Thiel V, Jores J, Drexler JF, Drosten C. Corman VM, et al. Among authors: thiel v. Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):9864-9. doi: 10.1073/pnas.1604472113. Epub 2016 Aug 15. Proc Natl Acad Sci U S A. 2016. PMID: 27528677 Free PMC article.
Attenuation of replication by a 29 nucleotide deletion in SARS-coronavirus acquired during the early stages of human-to-human transmission.
Muth D, Corman VM, Roth H, Binger T, Dijkman R, Gottula LT, Gloza-Rausch F, Balboni A, Battilani M, Rihtarič D, Toplak I, Ameneiros RS, Pfeifer A, Thiel V, Drexler JF, Müller MA, Drosten C. Muth D, et al. Among authors: thiel v. Sci Rep. 2018 Oct 11;8(1):15177. doi: 10.1038/s41598-018-33487-8. Sci Rep. 2018. PMID: 30310104 Free PMC article.
Inactivation of Severe Acute Respiratory Syndrome Coronavirus 2 by WHO-Recommended Hand Rub Formulations and Alcohols.
Kratzel A, Todt D, V'kovski P, Steiner S, Gultom M, Thao TTN, Ebert N, Holwerda M, Steinmann J, Niemeyer D, Dijkman R, Kampf G, Drosten C, Steinmann E, Thiel V, Pfaender S. Kratzel A, et al. Among authors: thiel v, v kovski p. Emerg Infect Dis. 2020 Jul;26(7):1592-1595. doi: 10.3201/eid2607.200915. Epub 2020 Jun 21. Emerg Infect Dis. 2020. PMID: 32284092 Free PMC article.
Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform.
Thi Nhu Thao T, Labroussaa F, Ebert N, V'kovski P, Stalder H, Portmann J, Kelly J, Steiner S, Holwerda M, Kratzel A, Gultom M, Schmied K, Laloli L, Hüsser L, Wider M, Pfaender S, Hirt D, Cippà V, Crespo-Pomar S, Schröder S, Muth D, Niemeyer D, Corman VM, Müller MA, Drosten C, Dijkman R, Jores J, Thiel V. Thi Nhu Thao T, et al. Among authors: thiel v, v kovski p. Nature. 2020 Jun;582(7813):561-565. doi: 10.1038/s41586-020-2294-9. Epub 2020 May 4. Nature. 2020. PMID: 32365353
315 results