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Elevated CD47 is a hallmark of dysfunctional aged muscle stem cells that can be targeted to augment regeneration.
Porpiglia E, Mai T, Kraft P, Holbrook CA, de Morree A, Gonzalez VD, Hilgendorf KI, Frésard L, Trejo A, Bhimaraju S, Jackson PK, Fantl WJ, Blau HM. Porpiglia E, et al. Among authors: de morree a. Cell Stem Cell. 2022 Dec 1;29(12):1653-1668.e8. doi: 10.1016/j.stem.2022.10.009. Epub 2022 Nov 15. Cell Stem Cell. 2022. PMID: 36384141 Free PMC article.
Regulation of adult stem cell function by ketone bodies.
Andersen OE, Poulsen JV, Farup J, de Morree A. Andersen OE, et al. Among authors: de morree a. Front Cell Dev Biol. 2023 Aug 31;11:1246998. doi: 10.3389/fcell.2023.1246998. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 37745291 Free PMC article. Review.
Extruded alginate tubes with myogenic potential.
Lenneman CM, Rose EM, Strawska BA, Tyszkiewicz NA, Dean-Christie K, Katz E, Roche JM, de Morree A, Roche R, Tulapurkar ME, Roche JA. Lenneman CM, et al. Among authors: de morree a. bioRxiv [Preprint]. 2024 May 3:2024.04.30.591971. doi: 10.1101/2024.04.30.591971. bioRxiv. 2024. PMID: 38746385 Free PMC article. Preprint.
Multiomics reveals glutathione metabolism as a driver of bimodality during stem cell aging.
Benjamin DI, Brett JO, Both P, Benjamin JS, Ishak HL, Kang J, Kim S, Chung M, Arjona M, Nutter CW, Tan JH, Krishnan AK, Dulay H, Louie SM, de Morree A, Nomura DK, Rando TA. Benjamin DI, et al. Among authors: de morree a. Cell Metab. 2023 Mar 7;35(3):472-486.e6. doi: 10.1016/j.cmet.2023.02.001. Epub 2023 Feb 27. Cell Metab. 2023. PMID: 36854304 Free PMC article.
Fasting induces a highly resilient deep quiescent state in muscle stem cells via ketone body signaling.
Benjamin DI, Both P, Benjamin JS, Nutter CW, Tan JH, Kang J, Machado LA, Klein JDD, de Morree A, Kim S, Liu L, Dulay H, Feraboli L, Louie SM, Nomura DK, Rando TA. Benjamin DI, et al. Among authors: de morree a. Cell Metab. 2022 Jun 7;34(6):902-918.e6. doi: 10.1016/j.cmet.2022.04.012. Epub 2022 May 17. Cell Metab. 2022. PMID: 35584694 Free PMC article.
38 results