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Transcriptome-wide association study and eQTL colocalization identify potentially causal genes responsible for human bone mineral density GWAS associations.
Al-Barghouthi BM, Rosenow WT, Du KP, Heo J, Maynard R, Mesner L, Calabrese G, Nakasone A, Senwar B, Gerstenfeld L, Larner J, Ferguson V, Ackert-Bicknell C, Morgan E, Brautigan D, Farber CR. Al-Barghouthi BM, et al. Among authors: farber cr. Elife. 2022 Nov 23;11:e77285. doi: 10.7554/eLife.77285. Elife. 2022. PMID: 36416764 Free PMC article.
Mouse genome-wide association and systems genetics identify Asxl2 as a regulator of bone mineral density and osteoclastogenesis.
Farber CR, Bennett BJ, Orozco L, Zou W, Lira A, Kostem E, Kang HM, Furlotte N, Berberyan A, Ghazalpour A, Suwanwela J, Drake TA, Eskin E, Wang QT, Teitelbaum SL, Lusis AJ. Farber CR, et al. PLoS Genet. 2011 Apr;7(4):e1002038. doi: 10.1371/journal.pgen.1002038. Epub 2011 Apr 7. PLoS Genet. 2011. PMID: 21490954 Free PMC article.
Systems genetic analysis of osteoblast-lineage cells.
Calabrese G, Bennett BJ, Orozco L, Kang HM, Eskin E, Dombret C, De Backer O, Lusis AJ, Farber CR. Calabrese G, et al. Among authors: farber cr. PLoS Genet. 2012;8(12):e1003150. doi: 10.1371/journal.pgen.1003150. Epub 2012 Dec 27. PLoS Genet. 2012. PMID: 23300464 Free PMC article.
Trps1 differentially modulates the bone mineral density between male and female mice and its polymorphism associates with BMD differently between women and men.
Wang L, Lu W, Zhang L, Huang Y, Scheib R, Liu X, Myers L, Lu L, Farber CR, Liu G, Wang CY, Deng H, Williams RW, Wang Y, Gu W, Jiao Y. Wang L, et al. Among authors: farber cr. PLoS One. 2014 Jan 8;9(1):e84485. doi: 10.1371/journal.pone.0084485. eCollection 2014. PLoS One. 2014. PMID: 24416236 Free PMC article.
Bicc1 is a genetic determinant of osteoblastogenesis and bone mineral density.
Mesner LD, Ray B, Hsu YH, Manichaikul A, Lum E, Bryda EC, Rich SS, Rosen CJ, Criqui MH, Allison M, Budoff MJ, Clemens TL, Farber CR. Mesner LD, et al. Among authors: farber cr. J Clin Invest. 2014 Jun;124(6):2736-49. doi: 10.1172/JCI73072. Epub 2014 May 1. J Clin Invest. 2014. PMID: 24789909 Free PMC article.
Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture.
Zheng HF, Forgetta V, Hsu YH, Estrada K, Rosello-Diez A, Leo PJ, Dahia CL, Park-Min KH, Tobias JH, Kooperberg C, Kleinman A, Styrkarsdottir U, Liu CT, Uggla C, Evans DS, Nielson CM, Walter K, Pettersson-Kymmer U, McCarthy S, Eriksson J, Kwan T, Jhamai M, Trajanoska K, Memari Y, Min J, Huang J, Danecek P, Wilmot B, Li R, Chou WC, Mokry LE, Moayyeri A, Claussnitzer M, Cheng CH, Cheung W, Medina-Gómez C, Ge B, Chen SH, Choi K, Oei L, Fraser J, Kraaij R, Hibbs MA, Gregson CL, Paquette D, Hofman A, Wibom C, Tranah GJ, Marshall M, Gardiner BB, Cremin K, Auer P, Hsu L, Ring S, Tung JY, Thorleifsson G, Enneman AW, van Schoor NM, de Groot LC, van der Velde N, Melin B, Kemp JP, Christiansen C, Sayers A, Zhou Y, Calderari S, van Rooij J, Carlson C, Peters U, Berlivet S, Dostie J, Uitterlinden AG, Williams SR, Farber C, Grinberg D, LaCroix AZ, Haessler J, Chasman DI, Giulianini F, Rose LM, Ridker PM, Eisman JA, Nguyen TV, Center JR, Nogues X, Garcia-Giralt N, Launer LL, Gudnason V, Mellström D, Vandenput L, Amin N, van Duijn CM, Karlsson MK, Ljunggren Ö, Svensson O, Hallmans G, Rousseau F, Giroux S, Bussière J, Arp PP, Koromani F, Prince RL, Lewis JR, Langdahl BL, Hermann AP, Jensen JE, Kapto… See abstract for full author list ➔ Zheng HF, et al. Nature. 2015 Oct 1;526(7571):112-7. doi: 10.1038/nature14878. Epub 2015 Sep 14. Nature. 2015. PMID: 26367794 Free PMC article.
126 results