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Antiviral signalling by a cyclic nucleotide activated CRISPR protease.
Rouillon C, Schneberger N, Chi H, Blumenstock K, Da Vela S, Ackermann K, Moecking J, Peter MF, Boenigk W, Seifert R, Bode BE, Schmid-Burgk JL, Svergun D, Geyer M, White MF, Hagelueken G. Rouillon C, et al. Among authors: moecking j. Nature. 2023 Feb;614(7946):168-174. doi: 10.1038/s41586-022-05571-7. Epub 2022 Nov 24. Nature. 2023. PMID: 36423657
Structural and mechanistic analysis of a tripartite ATP-independent periplasmic TRAP transporter.
Peter MF, Ruland JA, Depping P, Schneberger N, Severi E, Moecking J, Gatterdam K, Tindall S, Durand A, Heinz V, Siebrasse JP, Koenig PA, Geyer M, Ziegler C, Kubitscheck U, Thomas GH, Hagelueken G. Peter MF, et al. Among authors: moecking j. Nat Commun. 2022 Aug 4;13(1):4471. doi: 10.1038/s41467-022-31907-y. Nat Commun. 2022. PMID: 35927235 Free PMC article.
Pyroptosis inhibiting nanobodies block Gasdermin D pore formation.
Kopp A, Hagelueken G, Jamitzky I, Moecking J, Schiffelers LDJ, Schmidt FI, Geyer M. Kopp A, et al. Among authors: moecking j. Nat Commun. 2023 Dec 1;14(1):7923. doi: 10.1038/s41467-023-43707-z. Nat Commun. 2023. PMID: 38040708 Free PMC article.
NLRP1 variant M1184V decreases inflammasome activation in the context of DPP9 inhibition and asthma severity.
Moecking J, Laohamonthonkul P, Chalker K, White MJ, Harapas CR, Yu CH, Davidson S, Hrovat-Schaale K, Hu D, Eng C, Huntsman S, Calleja DJ, Horvat JC, Hansbro PM, O'Donoghue RJJ, Ting JP, Burchard EG, Geyer M, Gerlic M, Masters SL. Moecking J, et al. J Allergy Clin Immunol. 2021 Jun;147(6):2134-2145.e20. doi: 10.1016/j.jaci.2020.12.636. Epub 2020 Dec 27. J Allergy Clin Immunol. 2021. PMID: 33378691 Free PMC article.
15 results