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Page 1
Respiratory Effects of Biased Ligand Oliceridine in Older Volunteers: A Pharmacokinetic-Pharmacodynamic Comparison with Morphine.
Simons P, van der Schrier R, van Lemmen M, Jansen S, Kuijpers KWK, van Velzen M, Sarton E, Nicklas T, Michalsky C, Demitrack MA, Fossler M, Olofsen E, Niesters M, Dahan A. Simons P, et al. Among authors: michalsky c. Anesthesiology. 2023 Mar 1;138(3):249-263. doi: 10.1097/ALN.0000000000004473. Anesthesiology. 2023. PMID: 36538359 Free article. Clinical Trial.
The effect of TRV027 on coagulation in COVID-19: A pilot randomized, placebo-controlled trial.
Robbins AJ, Che Bakri NA, Toke-Bjolgerud E, Edwards A, Vikraman A, Michalsky C, Fossler M, Lemm NM, Medhipour S, Budd W, Gravani A, Hurley L, Kapil V, Jackson A, Lonsdale D, Latham V, Laffan M, Chapman N, Cooper N, Szydlo R, Boyle J, Pollock KM, Owen D. Robbins AJ, et al. Among authors: michalsky c. Br J Clin Pharmacol. 2023 Apr;89(4):1495-1501. doi: 10.1111/bcp.15618. Epub 2022 Dec 14. Br J Clin Pharmacol. 2023. PMID: 36437688 Free PMC article. Clinical Trial.
Low Incidence of Opioid-Induced Respiratory Depression Observed with Oliceridine Regardless of Age or Body Mass Index: Exploratory Analysis from a Phase 3 Open-Label Trial in Postsurgical Pain.
Brzezinski M, Hammer GB, Candiotti KA, Bergese SD, Pan PH, Bourne MH, Michalsky C, Wase L, Demitrack MA, Habib AS. Brzezinski M, et al. Among authors: michalsky c. Pain Ther. 2021 Jun;10(1):457-473. doi: 10.1007/s40122-020-00232-x. Epub 2021 Jan 21. Pain Ther. 2021. PMID: 33502739 Free PMC article.
Oliceridine is Associated with Reduced Risk of Vomiting and Need for Rescue Antiemetics Compared to Morphine: Exploratory Analysis from Two Phase 3 Randomized Placebo and Active Controlled Trials.
Beard TL, Michalsky C, Candiotti KA, Rider P, Wase L, Habib AS, Demitrack MA, Fossler MJ, Viscusi ER. Beard TL, et al. Among authors: michalsky c. Pain Ther. 2021 Jun;10(1):401-413. doi: 10.1007/s40122-020-00216-x. Epub 2020 Nov 18. Pain Ther. 2021. PMID: 33210266 Free PMC article.
Evaluating the Incidence of Opioid-Induced Respiratory Depression Associated with Oliceridine and Morphine as Measured by the Frequency and Average Cumulative Duration of Dosing Interruption in Patients Treated for Acute Postoperative Pain.
Ayad S, Demitrack MA, Burt DA, Michalsky C, Wase L, Fossler MJ, Khanna AK. Ayad S, et al. Among authors: michalsky c. Clin Drug Investig. 2020 Aug;40(8):755-764. doi: 10.1007/s40261-020-00936-0. Clin Drug Investig. 2020. PMID: 32583295 Free PMC article.