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The Swiss Pathogen Surveillance Platform - towards a nation-wide One Health data exchange platform for bacterial, viral and fungal genomics and associated metadata.
Neves A, Walther D, Martin-Campos T, Barbie V, Bertelli C, Blanc D, Bouchet G, Erard F, Greub G, Hirsch HH, Huber M, Kaiser L, Leib SL, Leuzinger K, Lazarevic V, Mäusezahl M, Molina J, Neher RA, Perreten V, Ramette A, Roloff T, Schrenzel J, Seth-Smith HMB, Stephan R, Terumalai D, Wegner F, Egli A. Neves A, et al. Among authors: neher ra. Microb Genom. 2023 May;9(5):mgen001001. doi: 10.1099/mgen.0.001001. Microb Genom. 2023. PMID: 37171846 Free PMC article.
A pseudovirus system enables deep mutational scanning of the full SARS-CoV-2 spike.
Dadonaite B, Crawford KHD, Radford CE, Farrell AG, Yu TC, Hannon WW, Zhou P, Andrabi R, Burton DR, Liu L, Ho DD, Chu HY, Neher RA, Bloom JD. Dadonaite B, et al. Among authors: neher ra. Cell. 2023 Mar 16;186(6):1263-1278.e20. doi: 10.1016/j.cell.2023.02.001. Epub 2023 Feb 13. Cell. 2023. PMID: 36868218 Free PMC article.
SARS-CoV-2 infection in immunosuppression evolves sub-lineages which independently accumulate neutralization escape mutations.
Lustig G, Ganga Y, Rodel HE, Tegally H, Khairallah A, Jackson L, Cele S, Khan K, Jule Z, Reedoy K, Karim F, Bernstein M, Ndung'u T, Moosa MS, Archary D, de Oliveira T, Lessells R, Neher RA, Abdool Karim SS, Sigal A. Lustig G, et al. Among authors: neher ra. Virus Evol. 2023 Dec 28;10(1):vead075. doi: 10.1093/ve/vead075. eCollection 2024. Virus Evol. 2023. PMID: 38361824 Free PMC article.
Revitalizing antibiotic discovery and development through in vitro modelling of in-patient conditions.
Sollier J, Basler M, Broz P, Dittrich PS, Drescher K, Egli A, Harms A, Hierlemann A, Hiller S, King CG, McKinney JD, Moran-Gilad J, Neher RA, Page MGP, Panke S, Persat A, Picotti P, Rentsch KM, Rivera-Fuentes P, Sauer U, Stolz D, Tschudin-Sutter S, van Delden C, van Nimwegen E, Veening JW, Zampieri M, Zinkernagel AS, Khanna N, Bumann D, Jenal U, Dehio C. Sollier J, et al. Among authors: neher ra. Nat Microbiol. 2024 Jan;9(1):1-3. doi: 10.1038/s41564-023-01566-w. Nat Microbiol. 2024. PMID: 38177300 No abstract available.
Evolution and neutralization escape of the SARS-CoV-2 BA.2.86 subvariant.
Khan K, Lustig G, Römer C, Reedoy K, Jule Z, Karim F, Ganga Y, Bernstein M, Baig Z, Jackson L, Mahlangu B, Mnguni A, Nzimande A, Stock N, Kekana D, Ntozini B, van Deventer C, Marshall T, Manickchund N, Gosnell BI, Lessells RJ, Karim QA, Abdool Karim SS, Moosa MS, de Oliveira T, von Gottberg A, Wolter N, Neher RA, Sigal A. Khan K, et al. Among authors: neher ra. Nat Commun. 2023 Dec 6;14(1):8078. doi: 10.1038/s41467-023-43703-3. Nat Commun. 2023. PMID: 38057313 Free PMC article.
APOBEC3 deaminase editing in mpox virus as evidence for sustained human transmission since at least 2016.
O'Toole Á, Neher RA, Ndodo N, Borges V, Gannon B, Gomes JP, Groves N, King DJ, Maloney D, Lemey P, Lewandowski K, Loman N, Myers R, Omah IF, Suchard MA, Worobey M, Chand M, Ihekweazu C, Ulaeto D, Adetifa I, Rambaut A. O'Toole Á, et al. Among authors: neher ra. Science. 2023 Nov 3;382(6670):595-600. doi: 10.1126/science.adg8116. Epub 2023 Nov 2. Science. 2023. PMID: 37917680 Free PMC article.
98 results