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Geospatial and temporal mapping of detectable HIV-1 viral loads amid dolutegravir rollout in KwaZulu-Natal, South Africa.
Gounder L, Tomita A, Lessells R, Moodley S, Francois KL, Khan A, Pillay M, Manyana SC, Govender S, Govender K, Moodley P, Parboosing R, Msomi N, Tanser F, Naidoo K, Chimukangara B. Gounder L, et al. Among authors: lessells r. PLOS Glob Public Health. 2024 May 28;4(5):e0003224. doi: 10.1371/journal.pgph.0003224. eCollection 2024. PLOS Glob Public Health. 2024. PMID: 38805477 Free PMC article.
Population Effectiveness of Dolutegravir Implementation in Uganda - A Prospective Observational Cohort Study (DISCO): 48-week Results.
McCluskey SM, Muyindike WR, Nanfuka V, Omoding D, Komukama N, Barigye IT, Kansiime L, Tumusiime J, Aung TN, Stuckwisch A, Hedt-Gauthier B, Marconi VC, Moosa MS, Pillay D, Giandhari J, Lessells R, Gupta RK, Siedner MJ. McCluskey SM, et al. Among authors: lessells r. J Infect Dis. 2024 May 16:jiae260. doi: 10.1093/infdis/jiae260. Online ahead of print. J Infect Dis. 2024. PMID: 38748986
Clearance of persistent SARS-CoV-2 associates with increased neutralizing antibodies in advanced HIV disease post-ART initiation.
Karim F, Riou C, Bernstein M, Jule Z, Lustig G, van Graan S, Keeton RS, Upton JL, Ganga Y, Khan K, Reedoy K, Mazibuko M, Govender K, Thambu K, Ngcobo N, Venter E, Makhado Z, Hanekom W, von Gottberg A, Hoque M, Karim QA, Abdool Karim SS, Manickchund N, Magula N, Gosnell BI, Lessells RJ, Moore PL, Burgers WA, de Oliveira T, Moosa MS, Sigal A. Karim F, et al. Among authors: lessells rj. Nat Commun. 2024 Mar 15;15(1):2360. doi: 10.1038/s41467-024-46673-2. Nat Commun. 2024. PMID: 38491050 Free PMC article.
Viremia and HIV Drug Resistance Among People Receiving Dolutegravir Versus Efavirenz-Based First-Line Antiretroviral Therapy.
Dorward J, Sookrajh Y, Lessells R, Bulo E, Bodley N, Singh L, Moodley P, Samsunder N, Drain PK, Hayward G, Butler CC, Garrett N. Dorward J, et al. Among authors: lessells r. J Acquir Immune Defic Syndr. 2024 Apr 15;95(5):e8-e11. doi: 10.1097/QAI.0000000000003385. Epub 2024 Mar 11. J Acquir Immune Defic Syndr. 2024. PMID: 38489494 Free PMC article.
SARS-CoV-2 infection in immunosuppression evolves sub-lineages which independently accumulate neutralization escape mutations.
Lustig G, Ganga Y, Rodel HE, Tegally H, Khairallah A, Jackson L, Cele S, Khan K, Jule Z, Reedoy K, Karim F, Bernstein M, Ndung'u T, Moosa MS, Archary D, de Oliveira T, Lessells R, Neher RA, Abdool Karim SS, Sigal A. Lustig G, et al. Among authors: lessells r. Virus Evol. 2023 Dec 28;10(1):vead075. doi: 10.1093/ve/vead075. eCollection 2024. Virus Evol. 2023. PMID: 38361824 Free PMC article.
COVID-19 vaccine uptake and effectiveness by time since vaccination in the Western Cape province, South Africa: An observational cohort study during 2020-2022.
Kassanjee R, Davies MA, Heekes A, Mahomed H, Hawkridge AJ, Wolmarans M, Morden E, Jacobs T, Cohen C, Moultrie H, Lessells RJ, Van Der Walt N, Arendse JO, Goeiman H, Mudaly V, Wolter N, Walaza S, Jassat W, von Gottberg A, Hannan PL, Rousseau P, Feikin D, Cloete K, Boulle A. Kassanjee R, et al. Among authors: lessells rj. medRxiv [Preprint]. 2024 Jan 25:2024.01.24.24301721. doi: 10.1101/2024.01.24.24301721. medRxiv. 2024. PMID: 38343866 Free PMC article. Preprint.
An Oxford Nanopore Technology-Based Hepatitis B Virus Sequencing Protocol Suitable For Genomic Surveillance Within Clinical Diagnostic Settings.
Tshiabuila D, Choga W, James SE, Maponga T, Preiser W, van Zyl G, Moir M, van Wyk S, Giandhari J, Pillay S, Anyaneji UJ, Lessells RJ, Naidoo Y, Sanko TJ, Wilkinson E, Tegally H, Baxter C, Martin DP, de Oliveira T. Tshiabuila D, et al. Among authors: lessells rj. medRxiv [Preprint]. 2024 Jan 25:2024.01.19.24301519. doi: 10.1101/2024.01.19.24301519. medRxiv. 2024. PMID: 38293032 Free PMC article. Preprint.
Clinical outcomes with second-line dolutegravir in people with virological failure on first-line non-nucleoside reverse transcriptase inhibitor-based regimens in South Africa: a retrospective cohort study.
Asare K, Sookrajh Y, van der Molen J, Khubone T, Lewis L, Lessells RJ, Naidoo K, Sosibo P, van Heerden R, Garrett N, Dorward J. Asare K, et al. Among authors: lessells rj. Lancet Glob Health. 2024 Feb;12(2):e282-e291. doi: 10.1016/S2214-109X(23)00516-8. Epub 2023 Dec 21. Lancet Glob Health. 2024. PMID: 38142692 Free PMC article.
Urine tenofovir and dried blood spot tenofovir diphosphate concentrations and viraemia in people taking efavirenz and dolutegravir-based antiretroviral therapy.
Dorward J, Govender K, Moodley P, Lessells R, Samsunder N, Sookrajh Y, Fanshawe TR, Turner PJ, Butler CC, Drain PK, Hayward GN, Garrett N. Dorward J, et al. Among authors: lessells r. AIDS. 2024 Apr 1;38(5):697-702. doi: 10.1097/QAD.0000000000003818. Epub 2024 Jan 8. AIDS. 2024. PMID: 38126342 Free PMC article.
161 results