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Mutant NPM1 Directly Regulates Oncogenic Transcription in Acute Myeloid Leukemia.
Uckelmann HJ, Haarer EL, Takeda R, Wong EM, Hatton C, Marinaccio C, Perner F, Rajput M, Antonissen NJC, Wen Y, Yang L, Brunetti L, Chen CW, Armstrong SA. Uckelmann HJ, et al. Among authors: chen cw. Cancer Discov. 2023 Mar 1;13(3):746-765. doi: 10.1158/2159-8290.CD-22-0366. Cancer Discov. 2023. PMID: 36455613 Free PMC article.
AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes.
Deshpande AJ, Deshpande A, Sinha AU, Chen L, Chang J, Cihan A, Fazio M, Chen CW, Zhu N, Koche R, Dzhekieva L, Ibáñez G, Dias S, Banka D, Krivtsov A, Luo M, Roeder RG, Bradner JE, Bernt KM, Armstrong SA. Deshpande AJ, et al. Among authors: chen l, chen cw. Cancer Cell. 2014 Dec 8;26(6):896-908. doi: 10.1016/j.ccell.2014.10.009. Epub 2014 Nov 20. Cancer Cell. 2014. PMID: 25464900 Free PMC article.
Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression in NPM1 Mutant Leukemia.
Kühn MW, Song E, Feng Z, Sinha A, Chen CW, Deshpande AJ, Cusan M, Farnoud N, Mupo A, Grove C, Koche R, Bradner JE, de Stanchina E, Vassiliou GS, Hoshii T, Armstrong SA. Kühn MW, et al. Among authors: chen cw. Cancer Discov. 2016 Oct;6(10):1166-1181. doi: 10.1158/2159-8290.CD-16-0237. Epub 2016 Aug 17. Cancer Discov. 2016. PMID: 27535106 Free PMC article.
Histone Acetyltransferase Activity of MOF Is Required for MLL-AF9 Leukemogenesis.
Valerio DG, Xu H, Chen CW, Hoshii T, Eisold ME, Delaney C, Cusan M, Deshpande AJ, Huang CH, Lujambio A, Zheng YG, Zuber J, Pandita TK, Lowe SW, Armstrong SA. Valerio DG, et al. Among authors: chen cw. Cancer Res. 2017 Apr 1;77(7):1753-1762. doi: 10.1158/0008-5472.CAN-16-2374. Epub 2017 Feb 15. Cancer Res. 2017. PMID: 28202522 Free PMC article.
2,045 results