Chi H - Search Results

1

CRISPR screens for functional interrogation of immunity.

Shi H, Doench JG, Chi H. Shi H, et al. Among authors: chi h. Nat Rev Immunol. 2023 Jun;23(6):363-380. doi: 10.1038/s41577-022-00802-4. Epub 2022 Dec 8. Nat Rev Immunol. 2023. PMID: 36481809 Review.

2

The receptor S1P1 overrides regulatory T cell-mediated immune suppression through Akt-mTOR.

Liu G, Burns S, Huang G, Boyd K, Proia RL, Flavell RA, Chi H. Liu G, et al. Among authors: chi h. Nat Immunol. 2009 Jul;10(7):769-77. doi: 10.1038/ni.1743. Epub 2009 May 31. Nat Immunol. 2009. PMID: 19483717 Free PMC article.

3

Signaling via the kinase p38α programs dendritic cells to drive TH17 differentiation and autoimmune inflammation.

Huang G, Wang Y, Vogel P, Kanneganti TD, Otsu K, Chi H. Huang G, et al. Among authors: chi h. Nat Immunol. 2012 Jan 8;13(2):152-61. doi: 10.1038/ni.2207. Nat Immunol. 2012. PMID: 22231518 Free PMC article.

4

Regulation and function of mTOR signalling in T cell fate decisions.

Chi H. Chi H. Nat Rev Immunol. 2012 Apr 20;12(5):325-38. doi: 10.1038/nri3198. Nat Rev Immunol. 2012. PMID: 22517423 Free PMC article. Review.

5

The kinase mTOR modulates the antibody response to provide cross-protective immunity to lethal infection with influenza virus.

Keating R, Hertz T, Wehenkel M, Harris TL, Edwards BA, McClaren JL, Brown SA, Surman S, Wilson ZS, Bradley P, Hurwitz J, Chi H, Doherty PC, Thomas PG, McGargill MA. Keating R, et al. Among authors: chi h. Nat Immunol. 2013 Dec;14(12):1266-76. doi: 10.1038/ni.2741. Epub 2013 Oct 20. Nat Immunol. 2013. PMID: 24141387 Free PMC article.

6

Mammalian Sterile 20-like Kinase 1 (Mst1) Enhances the Stability of Forkhead Box P3 (Foxp3) and the Function of Regulatory T Cells by Modulating Foxp3 Acetylation.

Li J, Du X, Shi H, Deng K, Chi H, Tao W. Li J, et al. Among authors: chi h. J Biol Chem. 2015 Dec 25;290(52):30762-70. doi: 10.1074/jbc.M115.668442. Epub 2015 Nov 3. J Biol Chem. 2015. PMID: 26538561 Free PMC article.

7

Discrete roles and bifurcation of PTEN signaling and mTORC1-mediated anabolic metabolism underlie IL-7-driven B lymphopoiesis.

Zeng H, Yu M, Tan H, Li Y, Su W, Shi H, Dhungana Y, Guy C, Neale G, Cloer C, Peng J, Wang D, Chi H. Zeng H, et al. Among authors: chi h. Sci Adv. 2018 Jan 31;4(1):eaar5701. doi: 10.1126/sciadv.aar5701. eCollection 2018 Jan. Sci Adv. 2018. PMID: 29399633 Free PMC article.

8

Hippo Kinases Mst1 and Mst2 Sense and Amplify IL-2R-STAT5 Signaling in Regulatory T Cells to Establish Stable Regulatory Activity.

Shi H, Liu C, Tan H, Li Y, Nguyen TM, Dhungana Y, Guy C, Vogel P, Neale G, Rankin S, Feng Y, Peng J, Tao W, Chi H. Shi H, et al. Among authors: chi h. Immunity. 2018 Nov 20;49(5):899-914.e6. doi: 10.1016/j.immuni.2018.10.010. Epub 2018 Nov 6. Immunity. 2018. PMID: 30413360 Free PMC article.

9

Metabolic coordination of T cell quiescence and activation.

Chapman NM, Boothby MR, Chi H. Chapman NM, et al. Among authors: chi h. Nat Rev Immunol. 2020 Jan;20(1):55-70. doi: 10.1038/s41577-019-0203-y. Epub 2019 Aug 12. Nat Rev Immunol. 2020. PMID: 31406325 Review.

10

Metabolic sleuthing solves a rare immunodeficiency disease.

Zeng H, Chi H. Zeng H, et al. Among authors: chi h. Nat Immunol. 2019 Oct;20(10):1264-1266. doi: 10.1038/s41590-019-0499-6. Nat Immunol. 2019. PMID: 31527832 No abstract available.

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