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A broadly reactive antibody targeting the N-terminal domain of SARS-CoV-2 spike confers Fc-mediated protection.
Cell Rep Med. 2023 Dec 19;4(12):101305. doi: 10.1016/j.xcrm.2023.101305. Epub 2023 Nov 30.
Cell Rep Med. 2023.
PMID: 38039973
Free PMC article.
Vertebrate-class-specific binding modes of the alphavirus receptor MXRA8.
Zimmerman O, Zimmerman MI, Raju S, Nelson CA, Errico JM, Madden EA, Holmes AC, Hassan AO, VanBlargan LA, Kim AS, Adams LJ, Basore K, Whitener BM, Palakurty S, Davis-Adams HG, Sun C, Gilliland T Jr, Earnest JT, Ma H, Ebel GD, Zmasek C, Scheuermann RH, Klimstra WB, Fremont DH, Diamond MS.
Zimmerman O, et al. Among authors: whitener bm.
Cell. 2023 Oct 26;186(22):4818-4833.e25. doi: 10.1016/j.cell.2023.09.007. Epub 2023 Oct 6.
Cell. 2023.
PMID: 37804831
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Fc-γR-dependent antibody effector functions are required for vaccine-mediated protection against antigen-shifted variants of SARS-CoV-2.
Mackin SR, Desai P, Whitener BM, Karl CE, Liu M, Baric RS, Edwards DK, Chicz TM, McNamara RP, Alter G, Diamond MS.
Mackin SR, et al. Among authors: whitener bm.
Nat Microbiol. 2023 Apr;8(4):569-580. doi: 10.1038/s41564-023-01359-1. Epub 2023 Apr 3.
Nat Microbiol. 2023.
PMID: 37012355
Free PMC article.
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prM-reactive antibodies reveal a role for partially mature virions in dengue virus pathogenesis.
Dowd KA, Sirohi D, Speer SD, VanBlargan LA, Chen RE, Mukherjee S, Whitener BM, Govero J, Aleshnick M, Larman B, Sukupolvi-Petty S, Sevvana M, Miller AS, Klose T, Zheng A, Koenig S, Kielian M, Kuhn RJ, Diamond MS, Pierson TC.
Dowd KA, et al. Among authors: whitener bm.
Proc Natl Acad Sci U S A. 2023 Jan 17;120(3):e2218899120. doi: 10.1073/pnas.2218899120. Epub 2023 Jan 13.
Proc Natl Acad Sci U S A. 2023.
PMID: 36638211
Free PMC article.
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Fcγ receptor-dependent antibody effector functions are required for vaccine protection against infection by antigenic variants of SARS-CoV-2.
Mackin SR, Desai P, Whitener BM, Karl CE, Liu M, Baric RS, Edwards DK, Chicz TM, McNamara RP, Alter G, Diamond MS.
Mackin SR, et al. Among authors: whitener bm.
bioRxiv [Preprint]. 2022 Nov 28:2022.11.27.518117. doi: 10.1101/2022.11.27.518117.
bioRxiv. 2022.
PMID: 36482975
Free PMC article.
Updated.
Preprint.
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Defining the risk of SARS-CoV-2 variants on immune protection.
DeGrace MM, Ghedin E, Frieman MB, Krammer F, Grifoni A, Alisoltani A, Alter G, Amara RR, Baric RS, Barouch DH, Bloom JD, Bloyet LM, Bonenfant G, Boon ACM, Boritz EA, Bratt DL, Bricker TL, Brown L, Buchser WJ, Carreño JM, Cohen-Lavi L, Darling TL, Davis-Gardner ME, Dearlove BL, Di H, Dittmann M, Doria-Rose NA, Douek DC, Drosten C, Edara VV, Ellebedy A, Fabrizio TP, Ferrari G, Fischer WM, Florence WC, Fouchier RAM, Franks J, García-Sastre A, Godzik A, Gonzalez-Reiche AS, Gordon A, Haagmans BL, Halfmann PJ, Ho DD, Holbrook MR, Huang Y, James SL, Jaroszewski L, Jeevan T, Johnson RM, Jones TC, Joshi A, Kawaoka Y, Kercher L, Koopmans MPG, Korber B, Koren E, Koup RA, LeGresley EB, Lemieux JE, Liebeskind MJ, Liu Z, Livingston B, Logue JP, Luo Y, McDermott AB, McElrath MJ, Meliopoulos VA, Menachery VD, Montefiori DC, Mühlemann B, Munster VJ, Munt JE, Nair MS, Netzl A, Niewiadomska AM, O'Dell S, Pekosz A, Perlman S, Pontelli MC, Rockx B, Rolland M, Rothlauf PW, Sacharen S, Scheuermann RH, Schmidt SD, Schotsaert M, Schultz-Cherry S, Seder RA, Sedova M, Sette A, Shabman RS, Shen X, Shi PY, Shukla M, Simon V, Stumpf S, Sullivan NJ, Thackray LB, Theiler J, Thomas PG, Trifkovic S, Türeli S, Turn…
See abstract for full author list ➔
DeGrace MM, et al. Among authors: whitener bm.
Nature. 2022 May;605(7911):640-652. doi: 10.1038/s41586-022-04690-5. Epub 2022 Mar 31.
Nature. 2022.
PMID: 35361968
Free PMC article.
Review.
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A potently neutralizing SARS-CoV-2 antibody inhibits variants of concern by utilizing unique binding residues in a highly conserved epitope.
VanBlargan LA, Adams LJ, Liu Z, Chen RE, Gilchuk P, Raju S, Smith BK, Zhao H, Case JB, Winkler ES, Whitener BM, Droit L, Aziati ID, Bricker TL, Joshi A, Shi PY, Creanga A, Pegu A, Handley SA, Wang D, Boon ACM, Crowe JE Jr, Whelan SPJ, Fremont DH, Diamond MS.
VanBlargan LA, et al. Among authors: whitener bm.
Immunity. 2021 Oct 12;54(10):2399-2416.e6. doi: 10.1016/j.immuni.2021.08.016. Epub 2021 Aug 19.
Immunity. 2021.
PMID: 34481543
Free PMC article.
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