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The SARS-CoV-2 spike S375F mutation characterizes the Omicron BA.1 variant.
Kimura I, Yamasoba D, Nasser H, Zahradnik J, Kosugi Y, Wu J, Nagata K, Uriu K, Tanaka YL, Ito J, Shimizu R, Tan TS, Butlertanaka EP, Asakura H, Sadamasu K, Yoshimura K, Ueno T, Takaori-Kondo A, Schreiber G; Genotype to Phenotype Japan (G2P-Japan) Consortium; Toyoda M, Shirakawa K, Irie T, Saito A, Nakagawa S, Ikeda T, Sato K. Kimura I, et al. Among authors: nagata k. iScience. 2022 Dec 22;25(12):105720. doi: 10.1016/j.isci.2022.105720. Epub 2022 Dec 5. iScience. 2022. PMID: 36507224 Free PMC article.
Abacavir, an anti-HIV-1 drug, targets TDP1-deficient adult T cell leukemia.
Tada K, Kobayashi M, Takiuchi Y, Iwai F, Sakamoto T, Nagata K, Shinohara M, Io K, Shirakawa K, Hishizawa M, Shindo K, Kadowaki N, Hirota K, Yamamoto J, Iwai S, Sasanuma H, Takeda S, Takaori-Kondo A. Tada K, et al. Among authors: nagata k. Sci Adv. 2015 Apr 24;1(3):e1400203. doi: 10.1126/sciadv.1400203. eCollection 2015 Apr. Sci Adv. 2015. PMID: 26601161 Free PMC article.
A screening for DNA damage response molecules that affect HIV-1 infection.
Yoshinaga N, Shindo K, Matsui Y, Takiuchi Y, Fukuda H, Nagata K, Shirakawa K, Kobayashi M, Takeda S, Takaori-Kondo A. Yoshinaga N, et al. Among authors: nagata k. Biochem Biophys Res Commun. 2019 May 21;513(1):93-98. doi: 10.1016/j.bbrc.2019.03.168. Epub 2019 Mar 30. Biochem Biophys Res Commun. 2019. PMID: 30935695 Free article.
Protein kinase A inhibits tumor mutator APOBEC3B through phosphorylation.
Matsumoto T, Shirakawa K, Yokoyama M, Fukuda H, Sarca AD, Koyabu S, Yamazaki H, Kazuma Y, Matsui H, Maruyama W, Nagata K, Tanabe F, Kobayashi M, Shindo K, Morishita R, Sato H, Takaori-Kondo A. Matsumoto T, et al. Among authors: nagata k. Sci Rep. 2019 Jun 5;9(1):8307. doi: 10.1038/s41598-019-44407-9. Sci Rep. 2019. PMID: 31165764 Free PMC article.
Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant.
Suzuki R, Yamasoba D, Kimura I, Wang L, Kishimoto M, Ito J, Morioka Y, Nao N, Nasser H, Uriu K, Kosugi Y, Tsuda M, Orba Y, Sasaki M, Shimizu R, Kawabata R, Yoshimatsu K, Asakura H, Nagashima M, Sadamasu K, Yoshimura K; Genotype to Phenotype Japan (G2P-Japan) Consortium; Sawa H, Ikeda T, Irie T, Matsuno K, Tanaka S, Fukuhara T, Sato K. Suzuki R, et al. Nature. 2022 Mar;603(7902):700-705. doi: 10.1038/s41586-022-04462-1. Epub 2022 Feb 1. Nature. 2022. PMID: 35104835 Free PMC article.
Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity.
Meng B, Abdullahi A, Ferreira IATM, Goonawardane N, Saito A, Kimura I, Yamasoba D, Gerber PP, Fatihi S, Rathore S, Zepeda SK, Papa G, Kemp SA, Ikeda T, Toyoda M, Tan TS, Kuramochi J, Mitsunaga S, Ueno T, Shirakawa K, Takaori-Kondo A, Brevini T, Mallery DL, Charles OJ; CITIID-NIHR BioResource COVID-19 Collaboration; Genotype to Phenotype Japan (G2P-Japan) Consortium; Ecuador-COVID19 Consortium; Bowen JE, Joshi A, Walls AC, Jackson L, Martin D, Smith KGC, Bradley J, Briggs JAG, Choi J, Madissoon E, Meyer KB, Mlcochova P, Ceron-Gutierrez L, Doffinger R, Teichmann SA, Fisher AJ, Pizzuto MS, de Marco A, Corti D, Hosmillo M, Lee JH, James LC, Thukral L, Veesler D, Sigal A, Sampaziotis F, Goodfellow IG, Matheson NJ, Sato K, Gupta RK. Meng B, et al. Nature. 2022 Mar;603(7902):706-714. doi: 10.1038/s41586-022-04474-x. Epub 2022 Feb 1. Nature. 2022. PMID: 35104837 Free PMC article.
3,502 results