Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

41 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
New Therapeutics in Alzheimer's Disease Longitudinal Cohort study (NTAD): study protocol.
Lanskey JH, Kocagoncu E, Quinn AJ, Cheng YJ, Karadag M, Pitt J, Lowe S, Perkinton M, Raymont V, Singh KD, Woolrich M, Nobre AC, Henson RN, Rowe JB; NTAD study group. Lanskey JH, et al. Among authors: perkinton m. BMJ Open. 2022 Dec 15;12(12):e055135. doi: 10.1136/bmjopen-2021-055135. BMJ Open. 2022. PMID: 36521898 Free PMC article.
P2X7R influences tau aggregate burden in human tauopathies and shows distinct signalling in microglia and astrocytes.
Beltran-Lobo P, Hughes MM, Troakes C, Croft CL, Rupawala H, Jutzi D, Ruepp MD, Jimenez-Sanchez M, Perkinton MS, Kassiou M, Golde TE, Hanger DP, Verkhratsky A, Perez-Nievas BG, Noble W. Beltran-Lobo P, et al. Among authors: perkinton ms. Brain Behav Immun. 2023 Nov;114:414-429. doi: 10.1016/j.bbi.2023.09.011. Epub 2023 Sep 15. Brain Behav Immun. 2023. PMID: 37716378 Free PMC article.
PrP is a central player in toxicity mediated by soluble aggregates of neurodegeneration-causing proteins.
Corbett GT, Wang Z, Hong W, Colom-Cadena M, Rose J, Liao M, Asfaw A, Hall TC, Ding L, DeSousa A, Frosch MP, Collinge J, Harris DA, Perkinton MS, Spires-Jones TL, Young-Pearse TL, Billinton A, Walsh DM. Corbett GT, et al. Among authors: perkinton ms. Acta Neuropathol. 2020 Mar;139(3):503-526. doi: 10.1007/s00401-019-02114-9. Epub 2019 Dec 18. Acta Neuropathol. 2020. PMID: 31853635 Free PMC article.
Preclinical development of a high affinity α-synuclein antibody, MEDI1341, that can enter the brain, sequester extracellular α-synuclein and attenuate α-synuclein spreading in vivo.
Schofield DJ, Irving L, Calo L, Bogstedt A, Rees G, Nuccitelli A, Narwal R, Petrone M, Roberts J, Brown L, Cusdin F, Dosanjh B, Lloyd C, Dobson C, Gurrell I, Fraser G, McFarlane M, Rockenstein E, Spencer B, Masliah E, Spillantini MG, Tan K, Billinton A, Vaughan T, Chessell I, Perkinton MS. Schofield DJ, et al. Among authors: perkinton ms. Neurobiol Dis. 2019 Dec;132:104582. doi: 10.1016/j.nbd.2019.104582. Epub 2019 Aug 21. Neurobiol Dis. 2019. PMID: 31445162 Free article.
Learnings about the complexity of extracellular tau aid development of a blood-based screen for Alzheimer's disease.
Chen Z, Mengel D, Keshavan A, Rissman RA, Billinton A, Perkinton M, Percival-Alwyn J, Schultz A, Properzi M, Johnson K, Selkoe DJ, Sperling RA, Patel P, Zetterberg H, Galasko D, Schott JM, Walsh DM. Chen Z, et al. Among authors: perkinton m. Alzheimers Dement. 2019 Mar;15(3):487-496. doi: 10.1016/j.jalz.2018.09.010. Epub 2018 Nov 9. Alzheimers Dement. 2019. PMID: 30419228 Free PMC article.
41 results