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Microglia ferroptosis is regulated by SEC24B and contributes to neurodegeneration.
Ryan SK, Zelic M, Han Y, Teeple E, Chen L, Sadeghi M, Shankara S, Guo L, Li C, Pontarelli F, Jensen EH, Comer AL, Kumar D, Zhang M, Gans J, Zhang B, Proto JD, Saleh J, Dodge JC, Savova V, Rajpal D, Ofengeim D, Hammond TR. Ryan SK, et al. Among authors: savova v. Nat Neurosci. 2023 Jan;26(1):12-26. doi: 10.1038/s41593-022-01221-3. Epub 2022 Dec 19. Nat Neurosci. 2023. PMID: 36536241 Free PMC article.
Molecular Features and Stages of Pulmonary Fibrosis Driven by Type 2 Inflammation.
Mattoo H, Bangari DS, Cummings S, Humulock Z, Habiel D, Xu EY, Pate N, Resnick R, Savova V, Qian G, Beil C, Rao E, Nestle FO, Bryce PJ, Subramaniam A. Mattoo H, et al. Among authors: savova v. Am J Respir Cell Mol Biol. 2023 Oct;69(4):404-421. doi: 10.1165/rcmb.2022-0301OC. Am J Respir Cell Mol Biol. 2023. PMID: 37369139
Additive efficacy of a bispecific anti-TNF/IL-6 nanobody compound in translational models of rheumatoid arthritis.
Biesemann N, Margerie D, Asbrand C, Rehberg M, Savova V, Agueusop I, Klemmer D, Ding-Pfennigdorff D, Schwahn U, Dudek M, Heyninck K, De Tavernier E, Cornelis S, Kohlmann M, Nestle FO, Herrmann M. Biesemann N, et al. Among authors: savova v. Sci Transl Med. 2023 Feb;15(681):eabq4419. doi: 10.1126/scitranslmed.abq4419. Epub 2023 Feb 1. Sci Transl Med. 2023. PMID: 36724239
Macrophage-Targeted Therapy Unlocks Antitumoral Cross-talk between IFNγ-Secreting Lymphocytes and IL12-Producing Dendritic Cells.
Pfirschke C, Zilionis R, Engblom C, Messemaker M, Zou AE, Rickelt S, Gort-Freitas NA, Lin Y, Bill R, Siwicki M, Gungabeesoon J, Sprachman MM, Marquard AN, Rodell CB, Cuccarese MF, Quintana J, Ahmed MS, Kohler RH, Savova V, Weissleder R, Klein AM, Pittet MJ. Pfirschke C, et al. Among authors: savova v. Cancer Immunol Res. 2022 Jan;10(1):40-55. doi: 10.1158/2326-6066.CIR-21-0326. Epub 2021 Dec 1. Cancer Immunol Res. 2022. PMID: 34795032 Free PMC article.
Identification of a targetable KRAS-mutant epithelial population in non-small cell lung cancer.
Maroni G, Bassal MA, Krishnan I, Fhu CW, Savova V, Zilionis R, Maymi VA, Pandell N, Csizmadia E, Zhang J, Storti B, Castaño J, Panella R, Li J, Gustafson CE, Fox S, Levy RD, Meyerovitz CV, Tramontozzi PJ, Vermilya K, De Rienzo A, Crucitta S, Bassères DS, Weetall M, Branstrom A, Giorgetti A, Ciampi R, Del Re M, Danesi R, Bizzarri R, Yang H, Kocher O, Klein AM, Welner RS, Bueno R, Magli MC, Clohessy JG, Ali A, Tenen DG, Levantini E. Maroni G, et al. Among authors: savova v. Commun Biol. 2021 Apr 14;4(1):370. doi: 10.1038/s42003-021-01897-6. Commun Biol. 2021. PMID: 33854168 Free PMC article.
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