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Differential diagnosis of bone marrow failure syndromes guided by machine learning.
Gutierrez-Rodrigues F, Munger E, Ma X, Groarke EM, Tang Y, Patel BA, Catto LFB, Clé DV, Niewisch MR, Alves-Paiva RM, Donaires FS, Pinto AL, Borges G, Santana BA, McReynolds LJ, Giri N, Altintas B, Fan X, Shalhoub R, Siwy CM, Diamond C, Raffo DQ, Craft K, Kajigaya S, Summers RM, Liu P, Cunningham L, Hickstein DD, Dunbar CE, Pasquini R, De Oliveira MM, Velloso EDRP, Alter BP, Savage SA, Bonfim C, Wu CO, Calado RT, Young NS. Gutierrez-Rodrigues F, et al. Among authors: fan x. Blood. 2023 Apr 27;141(17):2100-2113. doi: 10.1182/blood.2022017518. Blood. 2023. PMID: 36542832 Free PMC article.
The impact of aging on primate hematopoiesis as interrogated by clonal tracking.
Yu KR, Espinoza DA, Wu C, Truitt L, Shin TH, Chen S, Fan X, Yabe IM, Panch S, Hong SG, Koelle S, Lu R, Bonifacino A, Krouse A, Metzger M, Donahue RE, Dunbar CE. Yu KR, et al. Among authors: fan x. Blood. 2018 Mar 15;131(11):1195-1205. doi: 10.1182/blood-2017-08-802033. Epub 2018 Jan 2. Blood. 2018. PMID: 29295845 Free PMC article.
Treatment optimization and genomic outcomes in refractory severe aplastic anemia treated with eltrombopag.
Winkler T, Fan X, Cooper J, Desmond R, Young DJ, Townsley DM, Scheinberg P, Grasmeder S, Larochelle A, Desierto M, Valdez J, Lotter J, Wu C, Shalhoub RN, Calvo KR, Young NS, Dunbar CE. Winkler T, et al. Among authors: fan x. Blood. 2019 Jun 13;133(24):2575-2585. doi: 10.1182/blood.2019000478. Epub 2019 Apr 16. Blood. 2019. PMID: 30992268 Free PMC article. Clinical Trial.
Clonal tracking of erythropoiesis in rhesus macaques.
Fan X, Wu C, Truitt LL, Espinoza DA, Sellers S, Bonifacino A, Zhou Y, Cordes SF, Krouse A, Metzger M, Donahue RE, Lu R, Dunbar CE. Fan X, et al. Haematologica. 2020 Jul;105(7):1813-1824. doi: 10.3324/haematol.2019.231811. Epub 2019 Oct 3. Haematologica. 2020. PMID: 31582555 Free PMC article.
Eltrombopag for patients with moderate aplastic anemia or uni-lineage cytopenias.
Fan X, Desmond R, Winkler T, Young DJ, Dumitriu B, Townsley DM, Gutierrez-Rodrigues F, Lotter J, Valdez J, Sellers SE, Barranta ME, Shalhoub RN, Wu CO, Albitar M, Calvo KR, Young NS, Dunbar CE. Fan X, et al. Blood Adv. 2020 Apr 28;4(8):1700-1710. doi: 10.1182/bloodadvances.2020001657. Blood Adv. 2020. PMID: 32330244 Free PMC article. Clinical Trial.
Long-term eltrombopag for bone marrow failure depletes iron.
Young DJ, Fan X, Groarke EM, Patel B, Desmond R, Winkler T, Larochelle A, Calvo KR, Young NS, Dunbar CE. Young DJ, et al. Among authors: fan x. Am J Hematol. 2022 Jun 1;97(6):791-801. doi: 10.1002/ajh.26543. Epub 2022 Mar 26. Am J Hematol. 2022. PMID: 35312200 Free PMC article.
A macaque clonal hematopoiesis model demonstrates expansion of TET2-disrupted clones and utility for testing interventions.
Shin TH, Zhou Y, Chen S, Cordes S, Grice MZ, Fan X, Lee BC, Aljanahi AA, Hong SG, Vaughan KL, Mattison JA, Kohama SG, Fabre MA, Uchida N, Demirci S, Corat MAF, Métais JY, Calvo KR, Buscarlet M, Natanson H, McGraw KL, List AF, Busque L, Tisdale JF, Vassiliou GS, Yu KR, Dunbar CE. Shin TH, et al. Among authors: fan x. Blood. 2022 Oct 20;140(16):1774-1789. doi: 10.1182/blood.2021014875. Blood. 2022. PMID: 35714307 Free PMC article.
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