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Continuous blockade of CXCR4 results in dramatic mobilization and expansion of hematopoietic stem and progenitor cells.
Karpova D, Ritchey JK, Holt MS, Abou-Ezzi G, Monlish D, Batoon L, Millard S, Spohn G, Wiercinska E, Chendamarai E, Yang W, Christ S, Gehrs L, Schuettpelz LG, Dembowsky K, Pettit AR, Rettig MP, Bonig H, DiPersio JF. Karpova D, et al. Among authors: yang w. Blood. 2017 May 25;129(21):2939-2949. doi: 10.1182/blood-2016-10-746909. Epub 2017 Apr 11. Blood. 2017. PMID: 28400375 Free PMC article.
Targeting VLA4 integrin and CXCR2 mobilizes serially repopulating hematopoietic stem cells.
Karpova D, Rettig MP, Ritchey J, Cancilla D, Christ S, Gehrs L, Chendamarai E, Evbuomwan MO, Holt M, Zhang J, Abou-Ezzi G, Celik H, Wiercinska E, Yang W, Gao F, Eissenberg LG, Heier RF, Arnett SD, Meyers MJ, Prinsen MJ, Griggs DW, Trumpp A, Ruminski PG, Morrow DM, Bonig HB, Link DC, DiPersio JF. Karpova D, et al. Among authors: yang w. J Clin Invest. 2019 May 14;129(7):2745-2759. doi: 10.1172/JCI124738. J Clin Invest. 2019. PMID: 31085833 Free PMC article.
Macrophage NOX2 NADPH oxidase maintains alveolar homeostasis in mice.
Bhattacharya S, Idol RA, Yang W, Rojas Márquez JD, Li Y, Huang G, Beatty WL, Atkinson JJ, Brumell JH, Bagaitkar J, Magee JA, Dinauer MC. Bhattacharya S, et al. Among authors: yang w. Blood. 2022 May 12;139(19):2855-2870. doi: 10.1182/blood.2021015365. Blood. 2022. PMID: 35357446 Free PMC article.
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