Lei YL - Search Results

1

An epithelial-immune circuit amplifies inflammasome and IL-6 responses to SARS-CoV-2.

Barnett KC, Xie Y, Asakura T, Song D, Liang K, Taft-Benz SA, Guo H, Yang S, Okuda K, Gilmore RC, Loome JF, Oguin Iii TH, Sempowski GD, Randell SH, Heise MT, Lei YL, Boucher RC, Ting JP. Barnett KC, et al. Among authors: lei yl. Cell Host Microbe. 2023 Feb 8;31(2):243-259.e6. doi: 10.1016/j.chom.2022.12.005. Epub 2022 Dec 9. Cell Host Microbe. 2023. PMID: 36563691 Free PMC article.

2

NLRX1 is a regulator of mitochondrial antiviral immunity.

Moore CB, Bergstralh DT, Duncan JA, Lei Y, Morrison TE, Zimmermann AG, Accavitti-Loper MA, Madden VJ, Sun L, Ye Z, Lich JD, Heise MT, Chen Z, Ting JP. Moore CB, et al. Nature. 2008 Jan 31;451(7178):573-7. doi: 10.1038/nature06501. Epub 2008 Jan 16. Nature. 2008. PMID: 18200010

3

MAVS-mediated apoptosis and its inhibition by viral proteins.

Lei Y, Moore CB, Liesman RM, O'Connor BP, Bergstralh DT, Chen ZJ, Pickles RJ, Ting JP. Lei Y, et al. PLoS One. 2009;4(5):e5466. doi: 10.1371/journal.pone.0005466. Epub 2009 Mar 7. PLoS One. 2009. PMID: 19404494 Free PMC article.

4

How the noninflammasome NLRs function in the innate immune system.

Ting JP, Duncan JA, Lei Y. Ting JP, et al. Science. 2010 Jan 15;327(5963):286-90. doi: 10.1126/science.1184004. Science. 2010. PMID: 20075243 Free PMC article. Review.

5

Plexin-A4-semaphorin 3A signaling is required for Toll-like receptor- and sepsis-induced cytokine storm.

Wen H, Lei Y, Eun SY, Ting JP. Wen H, et al. J Exp Med. 2010 Dec 20;207(13):2943-57. doi: 10.1084/jem.20101138. Epub 2010 Nov 22. J Exp Med. 2010. PMID: 21098092 Free PMC article.

6

Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling.

Wen H, Gris D, Lei Y, Jha S, Zhang L, Huang MT, Brickey WJ, Ting JP. Wen H, et al. Nat Immunol. 2011 May;12(5):408-15. doi: 10.1038/ni.2022. Epub 2011 Apr 10. Nat Immunol. 2011. PMID: 21478880 Free PMC article.

7

NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-κB signaling pathways.

Allen IC, Moore CB, Schneider M, Lei Y, Davis BK, Scull MA, Gris D, Roney KE, Zimmermann AG, Bowzard JB, Ranjan P, Monroe KM, Pickles RJ, Sambhara S, Ting JP. Allen IC, et al. Immunity. 2011 Jun 24;34(6):854-65. doi: 10.1016/j.immuni.2011.03.026. Immunity. 2011. PMID: 21703540 Free PMC article.

8

The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy.

Lei Y, Wen H, Yu Y, Taxman DJ, Zhang L, Widman DG, Swanson KV, Wen KW, Damania B, Moore CB, Giguère PM, Siderovski DP, Hiscott J, Razani B, Semenkovich CF, Chen X, Ting JP. Lei Y, et al. Immunity. 2012 Jun 29;36(6):933-46. doi: 10.1016/j.immuni.2012.03.025. Immunity. 2012. PMID: 22749352 Free PMC article.

9

ASC-dependent RIP2 kinase regulates reduced PGE2 production in chronic periodontitis.

Taxman DJ, Lei Y, Zhang S, Holley-Guthrie E, Offenbacher S, Ting JP. Taxman DJ, et al. J Dent Res. 2012 Sep;91(9):877-82. doi: 10.1177/0022034512454541. Epub 2012 Jul 24. J Dent Res. 2012. PMID: 22828789 Free PMC article.

10

The NLR protein, NLRX1, and its partner, TUFM, reduce type I interferon, and enhance autophagy.

Lei Y, Wen H, Ting JP. Lei Y, et al. Autophagy. 2013 Mar;9(3):432-3. doi: 10.4161/auto.23026. Epub 2013 Jan 15. Autophagy. 2013. PMID: 23321557 Free PMC article.

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