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Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes.
Funsten MC, Yurkovetskiy LA, Kuznetsov A, Reiman D, Hansen CHF, Senter KI, Lee J, Ratiu J, Dahal-Koirala S, Antonopoulos DA, Dunny GM, Sollid LM, Serreze D, Khan AA, Chervonsky AV. Funsten MC, et al. Among authors: serreze d. Cell Host Microbe. 2023 Feb 8;31(2):213-227.e9. doi: 10.1016/j.chom.2022.12.009. Epub 2023 Jan 4. Cell Host Microbe. 2023. PMID: 36603588 Free PMC article.
B-lymphocytes expressing an Ig specificity recognizing the pancreatic ß-cell autoantigen peripherin are potent contributors to type 1 diabetes development in NOD mice.
Leeth CM, Racine J, Chapman HD, Arpa B, Carrillo J, Carrascal J, Wang Q, Ratiu J, Egia-Mendikute L, Rosell-Mases E, Stratmann T, Verdaguer J, Serreze DV. Leeth CM, et al. Among authors: serreze dv. Diabetes. 2016 Jul;65(7):1977-1987. doi: 10.2337/db15-1606. Epub 2016 Mar 9. Diabetes. 2016. PMID: 26961115 Free PMC article.
Genetic and Small Molecule Disruption of the AID/RAD51 Axis Similarly Protects Nonobese Diabetic Mice from Type 1 Diabetes through Expansion of Regulatory B Lymphocytes.
Ratiu JJ, Racine JJ, Hasham MG, Wang Q, Branca JA, Chapman HD, Zhu J, Donghia N, Philip V, Schott WH, Wasserfall C, Atkinson MA, Mills KD, Leeth CM, Serreze DV. Ratiu JJ, et al. Among authors: serreze dv. J Immunol. 2017 Jun 1;198(11):4255-4267. doi: 10.4049/jimmunol.1700024. Epub 2017 May 1. J Immunol. 2017. PMID: 28461573 Free PMC article.
169 results