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Single-cell transcriptomics reveals a mechanosensitive injury signaling pathway in early diabetic nephropathy.
Liu S, Zhao Y, Lu S, Zhang T, Lindenmeyer MT, Nair V, Gies SE, Wu G, Nelson RG, Czogalla J, Aypek H, Zielinski S, Liao Z, Schaper M, Fermin D, Cohen CD, Delic D, Krebs CF, Grahammer F, Wiech T, Kretzler M, Meyer-Schwesinger C, Bonn S, Huber TB. Liu S, et al. Among authors: krebs cf. Genome Med. 2023 Jan 10;15(1):2. doi: 10.1186/s13073-022-01145-4. Genome Med. 2023. PMID: 36627643 Free PMC article.
Angiotensin II type 2 receptor deficiency aggravates renal injury and reduces survival in chronic kidney disease in mice.
Benndorf RA, Krebs C, Hirsch-Hoffmann B, Schwedhelm E, Cieslar G, Schmidt-Haupt R, Steinmetz OM, Meyer-Schwesinger C, Thaiss F, Haddad M, Fehr S, Heilmann A, Helmchen U, Hein L, Ehmke H, Stahl RA, Böger RH, Wenzel UO. Benndorf RA, et al. Kidney Int. 2009 May;75(10):1039-49. doi: 10.1038/ki.2009.2. Epub 2009 Feb 11. Kidney Int. 2009. PMID: 19212419 Free article.
IL-17A production by renal γδ T cells promotes kidney injury in crescentic GN.
Turner JE, Krebs C, Tittel AP, Paust HJ, Meyer-Schwesinger C, Bennstein SB, Steinmetz OM, Prinz I, Magnus T, Korn T, Stahl RA, Kurts C, Panzer U. Turner JE, et al. J Am Soc Nephrol. 2012 Sep;23(9):1486-95. doi: 10.1681/ASN.2012010040. Epub 2012 Jul 12. J Am Soc Nephrol. 2012. PMID: 22797181 Free PMC article.
MicroRNA-155 drives TH17 immune response and tissue injury in experimental crescentic GN.
Krebs CF, Kapffer S, Paust HJ, Schmidt T, Bennstein SB, Peters A, Stege G, Brix SR, Meyer-Schwesinger C, Müller RU, Turner JE, Steinmetz OM, Wolf G, Stahl RA, Panzer U. Krebs CF, et al. J Am Soc Nephrol. 2013 Dec;24(12):1955-65. doi: 10.1681/ASN.2013020130. Epub 2013 Aug 15. J Am Soc Nephrol. 2013. PMID: 23949802 Free PMC article.
CXCL5 drives neutrophil recruitment in TH17-mediated GN.
Disteldorf EM, Krebs CF, Paust HJ, Turner JE, Nouailles G, Tittel A, Meyer-Schwesinger C, Stege G, Brix S, Velden J, Wiech T, Helmchen U, Steinmetz OM, Peters A, Bennstein SB, Kaffke A, Llanto C, Lira SA, Mittrücker HW, Stahl RA, Kurts C, Kaufmann SH, Panzer U. Disteldorf EM, et al. Among authors: krebs cf. J Am Soc Nephrol. 2015 Jan;26(1):55-66. doi: 10.1681/ASN.2013101061. Epub 2014 Jun 5. J Am Soc Nephrol. 2015. PMID: 24904089 Free PMC article.
CXCR3+ Regulatory T Cells Control TH1 Responses in Crescentic GN.
Paust HJ, Riedel JH, Krebs CF, Turner JE, Brix SR, Krohn S, Velden J, Wiech T, Kaffke A, Peters A, Bennstein SB, Kapffer S, Meyer-Schwesinger C, Wegscheid C, Tiegs G, Thaiss F, Mittrücker HW, Steinmetz OM, Stahl RA, Panzer U. Paust HJ, et al. Among authors: krebs cf. J Am Soc Nephrol. 2016 Jul;27(7):1933-42. doi: 10.1681/ASN.2015020203. Epub 2015 Nov 3. J Am Soc Nephrol. 2016. PMID: 26534920 Free PMC article.
Pathogen-induced tissue-resident memory TH17 (TRM17) cells amplify autoimmune kidney disease.
Krebs CF, Reimers D, Zhao Y, Paust HJ, Bartsch P, Nuñez S, Rosemblatt MV, Hellmig M, Kilian C, Borchers A, Enk LUB, Zinke M, Becker M, Schmid J, Klinge S, Wong MN, Puelles VG, Schmidt C, Bertram T, Stumpf N, Hoxha E, Meyer-Schwesinger C, Lindenmeyer MT, Cohen CD, Rink M, Kurts C, Franzenburg S, Koch-Nolte F, Turner JE, Riedel JH, Huber S, Gagliani N, Huber TB, Wiech T, Rohde H, Bono MR, Bonn S, Panzer U, Mittrücker HW. Krebs CF, et al. Sci Immunol. 2020 Aug 7;5(50):eaba4163. doi: 10.1126/sciimmunol.aba4163. Sci Immunol. 2020. PMID: 32769171
69 results