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Cross-Ancestry Genome-Wide Association Study Defines the Extended CYP2D6 Locus as the Principal Genetic Determinant of Endoxifen Plasma Concentrations.
Khor CC, Winter S, Sutiman N, Mürdter TE, Chen S, Lim JSL, Li Z, Li J, Sim KS, Ganchev B, Eccles D, Eccles B, Tapper W, Zgheib NK, Tfayli A, Ng RCH, Yap YS, Lim E, Wong M, Wong NS, Ang PCS, Dent R, Tremmel R, Klein K, Schaeffeler E, Zhou Y, Lauschke VM, Eichelbaum M, Schwab M, Brauch HB, Chowbay B, Schroth W. Khor CC, et al. Among authors: eichelbaum m. Clin Pharmacol Ther. 2023 Mar;113(3):712-723. doi: 10.1002/cpt.2846. Epub 2023 Jan 31. Clin Pharmacol Ther. 2023. PMID: 36629403
Pharmacogenomics of tamoxifen therapy.
Brauch H, Mürdter TE, Eichelbaum M, Schwab M. Brauch H, et al. Among authors: eichelbaum m. Clin Chem. 2009 Oct;55(10):1770-82. doi: 10.1373/clinchem.2008.121756. Epub 2009 Jul 2. Clin Chem. 2009. PMID: 19574470 Review.
Clinical Relevance of CYP2D6 Genetics for Tamoxifen Response in Breast Cancer.
Brauch H, Schroth W, Eichelbaum M, Schwab M, Harbeck N; in cooperation with the AGO TRAFO Comission. Brauch H, et al. Among authors: eichelbaum m. Breast Care (Basel). 2008;3(1):43-50. doi: 10.1159/000114642. Epub 2008 Feb 22. Breast Care (Basel). 2008. PMID: 20824020 Free PMC article.
Tamoxifen use in postmenopausal breast cancer: CYP2D6 matters.
Brauch H, Schroth W, Goetz MP, Mürdter TE, Winter S, Ingle JN, Schwab M, Eichelbaum M. Brauch H, et al. Among authors: eichelbaum m. J Clin Oncol. 2013 Jan 10;31(2):176-80. doi: 10.1200/JCO.2012.44.6625. Epub 2012 Oct 22. J Clin Oncol. 2013. PMID: 23091108 Free PMC article. No abstract available.
387 results