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Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor-reactive CD8+ T cells and reprogramming macrophages.
Immunity. 2023 Jan 10;56(1):162-179.e6. doi: 10.1016/j.immuni.2022.12.006.
Immunity. 2023.
PMID: 36630914
Free article.
Selective targeting of IL2Rβγ combined with radiotherapy triggers CD8- and NK-mediated immunity, abrogating metastasis in HNSCC.
Gadwa J, Amann M, Bickett TE, Knitz MW, Darragh LB, Piper M, Van Court B, Bukkapatnam S, Pham TT, Wang XJ, Saviola AJ, Deak LC, Umaña P, Klein C, D'Alessandro A, Karam SD.
Gadwa J, et al. Among authors: deak lc.
Cell Rep Med. 2023 Aug 15;4(8):101150. doi: 10.1016/j.xcrm.2023.101150.
Cell Rep Med. 2023.
PMID: 37586327
Free PMC article.
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Cell Squeeze: driving more effective CD8 T-cell activation through cytosolic antigen delivery.
Park JC, Bernstein H, Loughhead S, Zwirtes R, Jennings J, Nicolini V, Klein C, Deak LC, Umana P, Trumpfheller C, Sharei A.
Park JC, et al. Among authors: deak lc.
Immunooncol Technol. 2022 Jul 8;16:100091. doi: 10.1016/j.iotech.2022.100091. eCollection 2022 Dec.
Immunooncol Technol. 2022.
PMID: 36042779
Free PMC article.
Review.
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