Umaña P - Search Results

1

Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor-reactive CD8⁺ T cells and reprogramming macrophages.

Tichet M, Wullschleger S, Chryplewicz A, Fournier N, Marcone R, Kauzlaric A, Homicsko K, Deak LC, Umaña P, Klein C, Hanahan D. Tichet M, et al. Among authors: umana p. Immunity. 2023 Jan 10;56(1):162-179.e6. doi: 10.1016/j.immuni.2022.12.006. Immunity. 2023. PMID: 36630914 Free article.

2

GA201 (RG7160): a novel, humanized, glycoengineered anti-EGFR antibody with enhanced ADCC and superior in vivo efficacy compared with cetuximab.

Gerdes CA, Nicolini VG, Herter S, van Puijenbroek E, Lang S, Roemmele M, Moessner E, Freytag O, Friess T, Ries CH, Bossenmaier B, Mueller HJ, Umaña P. Gerdes CA, et al. Among authors: umana p. Clin Cancer Res. 2013 Mar 1;19(5):1126-38. doi: 10.1158/1078-0432.CCR-12-0989. Epub 2012 Dec 3. Clin Cancer Res. 2013. PMID: 23209031

3

Engineered glycoforms of an antineuroblastoma IgG1 with optimized antibody-dependent cellular cytotoxic activity.

Umaña P, Jean-Mairet J, Moudry R, Amstutz H, Bailey JE. Umaña P, et al. Nat Biotechnol. 1999 Feb;17(2):176-80. doi: 10.1038/6179. Nat Biotechnol. 1999. PMID: 10052355

4

Determination of antibody glycosylation by mass spectrometry.

Jäger C, Ferrara C, Umaña P, Zeck A, Regula JT, Koll H. Jäger C, et al. Among authors: umana p. Methods Mol Biol. 2012;901:195-208. doi: 10.1007/978-1-61779-931-0_13. Methods Mol Biol. 2012. PMID: 22723103

5

Tetracycline-regulated overexpression of glycosyltransferases in Chinese hamster ovary cells.

Umaña P, Jean-Mairet J, Bailey JE. Umaña P, et al. Biotechnol Bioeng. 1999 Dec 5;65(5):542-9. Biotechnol Bioeng. 1999. PMID: 10516580

6

Humanised IgG1 antibody variants targeting membrane-bound carcinoembryonic antigen by antibody-dependent cellular cytotoxicity and phagocytosis.

Ashraf SQ, Umana P, Mössner E, Ntouroupi T, Brünker P, Schmidt C, Wilding JL, Mortensen NJ, Bodmer WF. Ashraf SQ, et al. Among authors: umana p. Br J Cancer. 2009 Nov 17;101(10):1758-68. doi: 10.1038/sj.bjc.6605355. Br J Cancer. 2009. PMID: 19904275 Free PMC article.

7

Bispecific antibody derivatives with restricted binding functionalities that are activated by proteolytic processing.

Metz S, Panke C, Haas AK, Schanzer J, Lau W, Croasdale R, Hoffmann E, Schneider B, Auer J, Gassner C, Bossenmaier B, Umana P, Sustmann C, Brinkmann U. Metz S, et al. Among authors: umana p. Protein Eng Des Sel. 2012 Oct;25(10):571-80. doi: 10.1093/protein/gzs064. Epub 2012 Sep 13. Protein Eng Des Sel. 2012. PMID: 22976197 Free PMC article.

8

A novel combination of promoter and enhancers increases transgene expression in vascular smooth muscle cells in vitro and coronary arteries in vivo after adenovirus-mediated gene transfer.

Appleby CE, Kingston PA, David A, Gerdes CA, Umaña P, Castro MG, Lowenstein PR, Heagerty AM. Appleby CE, et al. Among authors: umana p. Gene Ther. 2003 Sep;10(18):1616-22. doi: 10.1038/sj.gt.3302044. Gene Ther. 2003. PMID: 12907954 Free PMC article.

9

A small-scale method for the preparation of plant N-linked glycans from soluble proteins for analysis by MALDI-TOF mass spectrometry.

Karg SR, Frey AD, Ferrara C, Streich DK, Umaña P, Kallio PT. Karg SR, et al. Among authors: umana p. Plant Physiol Biochem. 2009 Feb;47(2):160-6. doi: 10.1016/j.plaphy.2008.10.005. Epub 2008 Oct 26. Plant Physiol Biochem. 2009. PMID: 19028106

10

High-capacity, helper-dependent, "gutless" adenoviral vectors for gene transfer into brain.

Lowenstein PR, Thomas CE, Umana P, Gerdes CA, Verakis T, Boyer O, Tondeur S, Klatzmann D, Castro MG. Lowenstein PR, et al. Among authors: umana p. Methods Enzymol. 2002;346:292-311. doi: 10.1016/s0076-6879(02)46062-4. Methods Enzymol. 2002. PMID: 11883074 No abstract available.

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