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Inhibition of HSD17B13 protects against liver fibrosis by inhibition of pyrimidine catabolism in nonalcoholic steatohepatitis.
Luukkonen PK, Sakuma I, Gaspar RC, Mooring M, Nasiri A, Kahn M, Zhang XM, Zhang D, Sammalkorpi H, Penttilä AK, Orho-Melander M, Arola J, Juuti A, Zhang X, Yimlamai D, Yki-Järvinen H, Petersen KF, Shulman GI. Luukkonen PK, et al. Among authors: yimlamai d. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2217543120. doi: 10.1073/pnas.2217543120. Epub 2023 Jan 20. Proc Natl Acad Sci U S A. 2023. PMID: 36669104 Free PMC article.
Hepatocyte CYR61 polarizes profibrotic macrophages to orchestrate NASH fibrosis.
Mooring M, Yeung GA, Luukkonen P, Liu S, Akbar MW, Zhang GJ, Balogun O, Yu X, Mo R, Nejak-Bowen K, Poyurovsky MV, Booth CJ, Konnikova L, Shulman GI, Yimlamai D. Mooring M, et al. Among authors: yimlamai d. Sci Transl Med. 2023 Sep 27;15(715):eade3157. doi: 10.1126/scitranslmed.ade3157. Epub 2023 Sep 27. Sci Transl Med. 2023. PMID: 37756381 Free PMC article.
Immune landscape of human placental villi using single-cell analysis.
Toothaker JM, Olaloye O, McCourt BT, McCourt CC, Silva TN, Case RM, Liu P, Yimlamai D, Tseng G, Konnikova L. Toothaker JM, et al. Among authors: yimlamai d. Development. 2022 Apr 15;149(8):dev200013. doi: 10.1242/dev.200013. Epub 2022 Feb 17. Development. 2022. PMID: 35050308 Free PMC article.
Chitinase-3-like 1 protein complexes modulate macrophage-mediated immune suppression in glioblastoma.
Chen A, Jiang Y, Li Z, Wu L, Santiago U, Zou H, Cai C, Sharma V, Guan Y, McCarl LH, Ma J, Wu YL, Michel J, Shi Y, Konnikova L, Amankulor NM, Zinn PO, Kohanbash G, Agnihotri S, Lu S, Lu X, Sun D, Gittes GK, Wang Q, Xiao X, Yimlamai D, Pollack IF, Camacho CJ, Hu B. Chen A, et al. Among authors: yimlamai d. J Clin Invest. 2021 Aug 16;131(16):e147552. doi: 10.1172/JCI147552. J Clin Invest. 2021. PMID: 34228644 Free PMC article.
Loss of Anks6 leads to YAP deficiency and liver abnormalities.
Airik M, Schüler M, McCourt B, Weiss AC, Herdman N, Lüdtke TH, Widmeier E, Stolz DB, Nejak-Bowen KN, Yimlamai D, Wu YL, Kispert A, Airik R, Hildebrandt F. Airik M, et al. Among authors: yimlamai d. Hum Mol Genet. 2020 Nov 4;29(18):3064-3080. doi: 10.1093/hmg/ddaa197. Hum Mol Genet. 2020. PMID: 32886109 Free PMC article.
Targeting acid ceramidase inhibits YAP/TAZ signaling to reduce fibrosis in mice.
Alsamman S, Christenson SA, Yu A, Ayad NME, Mooring MS, Segal JM, Hu JK, Schaub JR, Ho SS, Rao V, Marlow MM, Turner SM, Sedki M, Pantano L, Ghoshal S, Ferreira DDS, Ma HY, Duwaerts CC, Espanol-Suner R, Wei L, Newcomb B, Mileva I, Canals D, Hannun YA, Chung RT, Mattis AN, Fuchs BC, Tager AM, Yimlamai D, Weaver VM, Mullen AC, Sheppard D, Chen JY. Alsamman S, et al. Among authors: yimlamai d. Sci Transl Med. 2020 Aug 19;12(557):eaay8798. doi: 10.1126/scitranslmed.aay8798. Sci Transl Med. 2020. PMID: 32817366 Free PMC article.
Imaging Mass Spectrometry Reveals Tumor Metabolic Heterogeneity.
Zhang Y, Guillermier C, De Raedt T, Cox AG, Maertens O, Yimlamai D, Lun M, Whitney A, Maas RL, Goessling W, Cichowski K, Steinhauser ML. Zhang Y, et al. Among authors: yimlamai d. iScience. 2020 Aug 21;23(8):101355. doi: 10.1016/j.isci.2020.101355. Epub 2020 Jul 10. iScience. 2020. PMID: 32712466 Free PMC article.
The Protective Effects of Calcineurin on Pancreatitis in Mice Depend on the Cellular Source.
Wen L, Javed TA, Dobbs AK, Brown R, Niu M, Li L, Khalid A, Barakat MT, Xiao X, Yimlamai D, Konnikova L, Yu M, Byersdorfer CA, Husain SZ. Wen L, et al. Among authors: yimlamai d. Gastroenterology. 2020 Sep;159(3):1036-1050.e8. doi: 10.1053/j.gastro.2020.05.051. Epub 2020 May 20. Gastroenterology. 2020. PMID: 32445858 Free PMC article.
26 results