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Ionisation bias undermines the use of matrix-assisted laser desorption/ionisation for estimating peptide deamidation: Synthetic peptide studies demonstrate electrospray ionisation gives more reliable response ratios.
Simpson JP, Fascione M, Bergström E, Wilson J, Collins MJ, Penkman KEH, Thomas-Oates J. Simpson JP, et al. Rapid Commun Mass Spectrom. 2019 Jun 30;33(12):1049-1057. doi: 10.1002/rcm.8441. Rapid Commun Mass Spectrom. 2019. PMID: 30908787 Free PMC article.
A Tale of Two Bioconjugations: pH Controlled Divergent Reactivity of Protein α-oxo-Aldehydes in Competing α-oxo-Mannich and Catalyst-Free Aldol Ligations.
Keenan T, Spears RJ, Akkad S, Mahon CS, Hatton NE, Walton J, Noble A, Yates ND, Baumann CG, Parkin A, Signoret N, Fascione MA. Keenan T, et al. Among authors: fascione ma. ACS Chem Biol. 2021 Nov 19;16(11):2387-2400. doi: 10.1021/acschembio.1c00531. Epub 2021 Nov 9. ACS Chem Biol. 2021. PMID: 34751550 Free article.
46 results